Detection of osseous metastases of the spine: comparison of high resolution multi-detector-CT with MRI

European Journal of Radiology
Sonja Buhmann KirchhoffAndrea Baur-Melnyk

Abstract

The aim of the study was to evaluate the diagnostic accuracy of multi-slice-computed tomography (MDCT) for the detection of vertebral metastases in comparison to magnetic resonance imaging (MRI). In a retrospective analysis, 639 vertebral bodies of 41 patients with various histologically confirmed primary malignancies were analysed. The MDCT-images were acquired on a 16/64-row-MDCT scanner (Siemens Somatom Sensation 16/64). MRI was performed on 1.5 T scanners (SIEMENS Symphony/Sonata). The MDCT- and MRI-images were evaluated separately by two experienced radiologists in a consensus reading. The combination of MDCT and MRI in an expert reading including follow-up examinations and/or histology as well as clinical data served as the gold standard. 201/639 vertebral bodies were defined as metastatically affected by the gold standard. In MDCT 133/201 lesions, in MRI 198/201 lesions were detected. 68 vertebral bodies were false negative in MDCT, whereas 3 false negatives were found in MRI. 3 false positive results were obtained in MDCT, 5 in MRI. Sensitivity was significantly lower for MDCT (66.2%) than for MRI (98.5%) (p<0.0001). Specificity was not significantly different for both methods (MDCT: 99.3%; MRI: 98.9%). The diagnostic a...Continue Reading

References

Feb 1, 1986·AJR. American Journal of Roentgenology·R H DaffnerR L Schapiro
Feb 1, 1985·Radiology·J S SchreimanJ W Beabout
Apr 1, 1967·Clinical Radiology·G A EdelstynF S Grebbell
Nov 1, 1994·Radiology·L A MoulopoulosH I Libshitz
May 1, 1993·AJR. American Journal of Roentgenology·A RahmouniN Vasile
Jul 1, 1993·Radiology·M E SchweitzerL G Gomella
Jan 1, 1996·Acta Oncologica·T Möller
Mar 2, 1999·Journal of Computer Assisted Tomography·M M SteinbornM F Reiser
May 30, 2002·AJR. American Journal of Roentgenology·A H MahnkenR W Günther

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Citations

Aug 4, 2010·European Journal of Nuclear Medicine and Molecular Imaging·Bernd KlaeserThomas Krause
Feb 9, 2012·International Journal of Surgical Oncology·Lubdha M Shah, Karen L Salzman
Aug 24, 2010·AJR. American Journal of Roentgenology·Bahman Roudsari, Jeffrey G Jarvik
Jul 26, 2014·Emergency Medicine Clinics of North America·Umar A KhanMichael T McCurdy
Mar 19, 2014·La Radiologia medica·Riccardo Del VescovoBruno Beomonte Zobel
Oct 8, 2013·The British Journal of Radiology·S SahaG Gnanasegaran
Jun 30, 2011·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Giuseppe Roberto D'AgostinoMario Balducci
Sep 11, 2012·Cancer Treatment Reviews·Aashish D BhattShiao Y Woo
Oct 6, 2009·Seminars in Nuclear Medicine·Gopinath GnanasegaranIgnac Fogelman
May 28, 2011·Journal of Magnetic Resonance Imaging : JMRI·Lian-Ming WuJian-Rong Xu
Jul 24, 2015·AJR. American Journal of Roentgenology·Adam N WallaceJack W Jennings
Oct 16, 2015·Semergen·E Esteban-ZuberoF J Ruiz-Ruiz
Jun 30, 2009·European Journal of Radiology·Lars FischerPeter Schemmer
May 13, 2015·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Gianluigi GuarnieriMario Muto
Jun 27, 2018·Expert Review of Anticancer Therapy·Balamurugan A VellayappanSimon S Lo
Oct 30, 2018·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Katherine M Krajewski, Ivan Pedrosa
Nov 2, 2012·The Open Orthopaedics Journal·Permsak PaholpakPolasak Jeeravipoolvarn
Apr 26, 2019·Topics in Magnetic Resonance Imaging : TMRI·Majid KhanKristin Redmond
Apr 3, 2014·Iranian Red Crescent Medical Journal·Mahyar GhafooriMounes Aliyari Ghasabeh
Aug 4, 2020·Journal of Endocrinological Investigation·A NervoE Arvat
Jan 6, 2011·The Journal of the American Academy of Orthopaedic Surgeons·Peter S Rose, Jacob M Buchowski
Oct 1, 2020·Food Science & Nutrition·Xinhong LiuXin Zhao
Mar 17, 2019·European Radiology·Guillaume GravelFrederic Deschamps
Jul 1, 2020·Insights Into Imaging·Trinh T NguyenAlok A Bhatt
Sep 11, 2018·Journal of Clinical Imaging Science·Dinesh RaoSukhwinder Js Sandhu
May 17, 2017·Global Spine Journal·Chia-Lin TsengArjun Sahgal
May 7, 2013·Bulletin du cancer·Fahed ZairiRichard Assaker
Dec 11, 2020·Neuro-oncology Practice·Jeremy M SteinbergerIsabelle M Germano
Feb 24, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Jad S HusseiniOnofrio A Catalano
Jul 14, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Christof BoehmDimitrios C Karampinos

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