Detection of postural sway abnormalities by wireless inertial sensors in minimally disabled patients with multiple sclerosis: a case-control study

Journal of Neuroengineering and Rehabilitation
Andrew J SolomonSharon M Henry

Abstract

Common clinical neurological exams can be insensitive to balance and mobility impairment at the early stages of multiple sclerosis (MS) and may not correspond with patient reports. Instrumented measurement of standing postural sway with inertial motion sensors may provide sensitive measures of balance impairment and better correspond with patient reports. While wearing wireless inertial sensors, 20 subjects with MS - Expanded Disability Status Scale of less than 3.0 and a Timed 25 Foot Walk of 5 sec or less - and 20 age- and sex-matched control subjects stood with eyes open and eyes closed on a foam surface. Forty-six outcome measures of postural sway were derived. A stepwise logistic regression model determined which measures of instrumented sway provide independent predictors of group status. Subjects with MS also completed the Activities-Specific Balance Confidence (ABC) scale and the 12-Item MS Walking Scale (MSWS-12) as measures of subject-reported balance and mobility impairment. The regression model identified medio-lateral sway path length and medio-lateral range of sway acceleration amplitude, each in the eyes-open condition, as the only two significant independent predictors to differentiate subjects with MS from thos...Continue Reading

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Citations

Jun 17, 2016·Expert Review of Medical Devices·Marco IosaGiovanni Morone
Feb 17, 2018·Frontiers in Neurology·Camille J ShanahanScott C Kolbe
Sep 6, 2019·Current Neurology and Neuroscience Reports·Mikaela L FrechetteJacob J Sosnoff
May 24, 2017·Journal of Neuroengineering and Rehabilitation·Jordan J CraigJessie M Huisinga
May 7, 2020·Sensors·Carlos Cruz-MontecinosXavier García-Massó
Sep 25, 2019·Sensors·Marco GhislieriValentina Agostini

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