Detection of rifampicin resistance in tuberculosis by molecular methods: A report from Eastern Uttar Pradesh, India

Indian Journal of Medical Microbiology
R TripathiShampa Anupurba

Abstract

Diagnosis of drug resistance tuberculosis (TB) by the gold standard method is labour intensive and time consuming. Hence, there is an urgent need for introduction of rapid diagnostic techniques. Line probe assay (LPA) and cartridge-based nucleic acid amplification test (CBNAAT) have been introduced in India under Revised National Tuberculosis Control Program. Spot and morning sputum samples of previously treated patients by anti-TB drugs were subjected to LPA or CBNAAT. Total 682/1253 (54.4%) were diagnosed as rifampicin-resistant. The patients could be diagnosed early by molecular methods and put on second line treatment.

References

Jan 19, 2008·American Journal of Respiratory and Critical Care Medicine·Marinus BarnardMarlein E Bosman
Aug 15, 2014·Indian Journal of Pathology & Microbiology·Soniya SharmaAshish K Asthana
Apr 11, 2015·The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·P KumarS Singh

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Citations

Feb 7, 2018·Expert Review of Anti-infective Therapy·Rajeswari Ramachandran, M Muniyandi
Oct 5, 2019·The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale·Kibriti MehariMuthupandian Saravanan
Apr 23, 2020·Journal of Family Medicine and Primary Care·Mukesh SharmaSunil K Bhambu

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