Detection of significant residual stenosis of the infarct-related artery after thrombolysis by high-dose dipyridamole echocardiography test: is it detected often enough?

Clinical Cardiology
A N NeskovićA D Popović

Abstract

It has been reported that high-dose dipyridamole echocardiography test (DET) can be successfully used for the detection of critical residual stenosis of the infarct-related artery (IRA). However, we have recently noticed low sensitivity of DET for the detection of residual IRA stenosis in patients with single-vessel disease. This study sought to determine the value of DET for the detection of significant residual stenosis of the IRA after thrombolysis. Dipyridamole echocardiography test was performed in 55 consecutive patients after a first acute myocardial infarction before hospital discharge. All patients underwent coronary angiography 23 +/- 6 days after infarction. Nine of 19 patients with positive DET revealed new adjacent asynergy and all of the patients had patient and significantly stenotic IRA. Sensitivity and specificity of DET in identifying significant residual stenosis of the IRA were 24 and 100%, respectively. Among 49 patients with significantly stenotic of occluded IRA, 40 patients without adjacent asynergy during DET had higher baseline wall motion score index (WMSI) compared with 9 patients who revealed adjacent asynergy during DET (1.45 +/- 0.30 vs. 1.24 +/- 0.18; p < 0.05). When all patients with positive DE...Continue Reading

References

Mar 15, 1989·Annals of Internal Medicine·R F DeBusk
Sep 1, 1989·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·N B SchillerI Schnittger
Jul 1, 1986·Journal of the American College of Cardiology·K L Gould
Apr 4, 1985·The New England Journal of Medicine·UNKNOWN TIMI Study Group
Jan 1, 1982·Catheterization and Cardiovascular Diagnosis·J W Kennedy

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