Detection of small bioactive peptides from Atlantic herring (Clupea harengus L.)

Peptides
Daniela M PampaninMagne O Sydnes

Abstract

Recent research has shown that fish residual materials contain a range of components with interesting biological activity. Therefore, there is a great potential in the marine bioprocess industry to utilize these by-products as starting material for generating more valuable products. The aim of the present study was to search for bioactive peptides (in particular small natural bioactive peptides with molecular weight lower than 10 kDa) in Atlantic herring (Clupea harengus L.) by-products such as skin and more general residual materials. By such means a range of peptides with claimed interesting biological activities was found. Herein the activity of the detected bioactive peptides and strategies for isolating peptide fragments containing the bioactive motif is discussed. Identification of bioactive peptides in crude peptide/protein sources (skin and residual materials) was performed directly using a combination of mass spectrometry (Orbitrap), bioinformatics and database search. This method was a good angle of approach in order to map the potential in new species and species that have been very little studied.

References

Feb 16, 2000·Critical Reviews in Food Science and Nutrition·H G Kristinsson, B A Rasco
Jul 3, 2002·Journal of Peptide Science : an Official Publication of the European Peptide Society·Chun-Hui LiTerukazu Kawasaki
Jan 2, 2008·Journal of the American Chemical Society·Hyun-Woo RheeJong-In Hong
Feb 2, 2008·Journal of the American Chemical Society·Dowook RyuKyo Han Ahn
Feb 23, 2008·Organic & Biomolecular Chemistry·Hao WangAlbert W M Lee
Oct 15, 2008·Journal of the American Chemical Society·Xiaogang HanZhaoxiang Deng
Nov 26, 2010·Peptides·Venugopal Rajanbabu, Jyh-Yih Chen
Sep 1, 2006·Meat Science·Keizo Arihara
Jan 19, 2012·Nutrients·Joseph Thomas RyanCatherine Stanton

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Risk Reduction

Prevention of cardiovascular disease is an important health initiative. Risk reduction including physical activity, smoking cessation, diet, blood pressure lowering drugs and pharmacotherapy. Here is the latest research on cardiovascular risk reduction.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.