Detection of small inflammatory and metastatic lymph nodes in rabbits by sonography: evaluation with the resistive index ratio

Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Ying HuangFan-Hua Xu

Abstract

The aim of this prospective study was to determine whether the resistive index (RI) ratio based on high-resolution spectral Doppler sonography would be useful in the differential diagnosis of small inflammatory and metastatic lymph nodes in rabbit models. The infected and metastatic lymph node models we used were created by subcutaneously inoculating methicillin-susceptible Staphylococcus aureus and VX2 tumor cells respectively into the left hind limbs of 10 New Zealand White rabbits. High-resolution sonography was performed to investigate the popliteal fossa lymph nodes 2 weeks after the inoculation. The sizes, long-/short-axis ratios, and RI ratios (defined as the value of the peripheral RI relative to the central RI) of the nodes were evaluated with sonography and then compared with the histopathologic findings. No statistical differences were found between the volumes (mean +/- SD, 104 +/- 41 versus 87 +/- 24 mm(3); P > .05) and the long-/short-axis ratios (1.97 +/- 0.28 versus 2.03 +/- 0.26; P > .05) of 15 inflammatory and 14 metastatic lymph nodes. On spectral Doppler sonography, the RI ratio was higher in the metastatic lymph nodes than in the inflammatory lymph nodes. With an RI ratio higher than 1.2 as a diagnostic cri...Continue Reading

References

Nov 1, 1983·The Journal of Pathology·A M Schor, S L Schor
Mar 1, 1995·The British Journal of Radiology·H J SteinkampR Felix
Apr 1, 1994·AJR. American Journal of Roentgenology·D B ChangP C Yang
Jan 1, 1995·Ultrasound in Medicine & Biology·D S BellR J Eckersley
Nov 1, 1995·Journal of Clinical Ultrasound : JCU·S DelormeG van Kaick
Nov 1, 1995·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·W T YangC Metreweli
May 10, 2001·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·T ShirakawaS Tada
Apr 6, 2002·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Francesco GiovagnorioVincenzo David
Jan 2, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jean PalussièreChrit T W Moonen
Jan 24, 2003·European Radiology·Zoran Brnić, Andrija Hebrang
Apr 23, 2003·Ultrasound in Medicine & Biology·Anil Ahuja, Michael Ying
May 3, 2003·Clinical Radiology·A Ahuja, M Ying
May 4, 2004·Ultrasound in Medicine & Biology·Michael YingFiona Brook
Jul 13, 2004·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Leopoldo RubaltelliCarlo Riccardo Rossi
Apr 28, 2005·AJR. American Journal of Roentgenology·Anil T Ahuja, Michael Ying
Feb 17, 2006·European Journal of Radiology·Gul Esen
May 12, 2006·European Journal of Radiology·C KrestanC Czerny
Jan 26, 2007·European Radiology·Takashi Nakamura, Misa Sumi
Mar 31, 1940·The Journal of Experimental Medicine·J G Kidd, P Rous

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Citations

May 12, 2009·Ultrasound in Medicine & Biology·Mattéo R BosisioS Lori Bridal

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