Detection of subnanotesla oscillatory magnetic fields using MRI

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Xia JiangJia-Hong Gao

Abstract

Direct mapping of neuronal currents using MRI would have fundamental impacts on brain functional imaging. Previous reports indicated that the stimulus-induced rotary saturation (SIRS) mechanism had the best potential of direct detection of neural oscillations; however, it lacked the high-sensitivity level needed. In this study, a novel strategy is proposed in an effort to improve the detection sensitivity. In our modified SIRS sequence, an external oscillatory magnetic field is used as the excitation pulse in place of the standard 90-degree excitation pulse. This approach could potentially lead to tens or even hundreds times of enhancement in the detection sensitivity for low field signals. It also helps to lower the physiological noise, allows for shorter pulse repetition time, and is less affected by the blood oxygen level. We demonstrate that a 100-Hz oscillatory magnetic field with magnitude as low as 0.25 nanotesla generated in a current loop can be robustly detected using a 3-Tesla MRI scanner. The modified SIRS sequence offers higher detection sensitivity as well as several additional advantages. These promising results suggest that the direct detection of neural oscillation might be within the grasp of the current MRI t...Continue Reading

References

Dec 1, 1992·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G C ScottR M Henkelman
Apr 21, 1999·Brain Research. Brain Research Reviews·W Klimesch
Apr 27, 1999·Brain Topography·C CiullaH Endo
Nov 27, 1999·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·G Pfurtscheller, F H Lopes da Silva
Oct 9, 2001·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·G Krüger, G H Glover
Jul 12, 2002·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jerzy Bodurka, Peter A Bandettini
Dec 31, 2002·Brain Research. Brain Research Reviews·Kwang-Hyuk LeeEvian Gordon
Jun 20, 2003·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Daniel KonnRichard Bowtell
Apr 6, 2004·Journal of Magnetic Resonance Imaging : JMRI·Arijitt BorthakurRavinder Reddy
Aug 31, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Petr VolegovRobert H Kraus
Nov 25, 2004·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Andrew J WheatonRavinder Reddy
Feb 15, 2005·Magnetic Resonance Imaging·Daniel KonnRichard Bowtell
Apr 8, 2006·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gaby S PellGraeme D Jackson
Jan 30, 2007·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Laura M ParkesDavid G Norris
Feb 13, 2007·Journal of Magnetic Resonance·Walter R T WitscheyRavinder Reddy
Oct 16, 2007·Trends in Neurosciences·Alan Jasanoff
Jan 9, 2008·Magnetic Resonance Imaging·Lin TangJohn C Gore
Oct 29, 2008·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Li Sze ChowMartyn N J Paley
Apr 28, 2010·Proceedings of the National Academy of Sciences of the United States of America·Nicholas W Halpern-MannersAlexander Pines
Sep 2, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Padmavathi SundaramDarren B Orbach

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Citations

Jan 18, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Trong-Kha TruongAllen W Song
Apr 9, 2020·Journal of Neural Engineering·Bragi SveinssonMatthew S Rosen
Jan 23, 2021·Journal of Magnetic Resonance·Hiroyuki UedaTetsuo Kobayashi

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