Detection of Taenia solium taeniasis coproantigen is an early indicator of treatment failure for taeniasis.

Clinical and Vaccine Immunology : CVI
Javier A BustosCysticercosis Working Group in Perú

Abstract

Taenia solium causes taeniasis and cysticercosis, a zoonotic complex associated with a significant burden of epilepsy in most countries. Reliable diagnosis and efficacious treatment of taeniasis are needed for disease control. Currently, cure can be confirmed only after a period of at least 1 month, by negative stool microscopy. This study assessed the performance of detection by a coproantigen enzyme-linked immunosorbent assay (CoAg-ELISA) for the early evaluation of the efficacy of antiparasitic treatment of human T. solium taeniasis. We followed 69 tapeworm carriers who received niclosamide as standard treatment. Stool samples were collected on days 1, 3, 7, 15, 30, and 90 after treatment and were processed by microscopy and CoAg-ELISA. The efficacy of niclosamide was 77.9% (53/68). Thirteen patients received a second course of treatment and completed the follow-up. CoAg-ELISA was therefore evaluated for a total of 81 cases (68 treatments, 13 retreatments). In successful treatments (n = 64), the proportion of patients who became negative by CoAg-ELISA was 62.5% after 3 days, 89.1% after 7 days, 96.9% after 15 days, and 100% after 30 days. In treatment failures (n = 17), the CoAg-ELISA result was positive for 70.6% of patient...Continue Reading

References

Dec 1, 1990·Parasitology·J C AllanP S Craig
Apr 1, 1985·Annals of Internal Medicine·R D Pearson, E L Hewlett
Jan 1, 1972·Advances in Parasitology·Z Pawlowski, M G Schultz
Jul 1, 1970·The American Journal of Tropical Medicine and Hygiene·D R PereraM G Schultz
Apr 1, 1983·Medicinal Research Reviews·P AndrewsJ Seubert
Apr 1, 1996·The American Journal of Tropical Medicine and Hygiene·J C AllanJ Garcia-Noval
Apr 1, 1996·Annals of Tropical Medicine and Parasitology·J C AllanP S Craig
Mar 11, 1999·The American Journal of Tropical Medicine and Hygiene·P P WilkinsV C Tsang
Mar 30, 2000·Infectious Disease Clinics of North America·H H Garcia, O H Del Brutto
Sep 25, 2002·Microbes and Infection·Eric P Hoberg
Mar 13, 2003·Parasitology Research·Guillermina AvilaAna Flisser
Aug 23, 2003·Lancet·Héctor H GarcíaUNKNOWN Cysticercosis Working Group in Peru
Mar 27, 2004·Lancet·Cesar JeriHector H Garcia
Dec 1, 1993·Parasitology Today·Z S Pawlowski
Jan 13, 2005·Acta Neurologica Scandinavica·C DeGiorgioF Sorvillo
Jul 27, 2005·Neurology·S M MontanoUNKNOWN Cysticercosis Working Group in Peru
Jan 28, 2009·PLoS Neglected Tropical Diseases·Andres G LescanoUNKNOWN Cysticercosis Working Group in Peru
Nov 13, 2009·Clinical and Vaccine Immunology : CVI·Sukwan HandaliPatricia P Wilkins

❮ Previous
Next ❯

Citations

Aug 30, 2013·Parasitology·Francis RaoulAkira Ito
May 9, 2014·The American Journal of Tropical Medicine and Hygiene·Paul T CanteyTheodore E Nash
Jan 29, 2014·Tropical Parasitology·Subhash Chandra Parija, Dinoop Korol Ponnambath
Dec 30, 2014·Current Tropical Medicine Reports·Hélène Carabin, Aminata A Traoré
Aug 26, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Angélique LewiesDu Plessis Lissinda Hester
Jan 24, 2016·Acta Tropica·Hai-Wei WuArve Lee Willingham Iii
Nov 6, 2015·Parasite Immunology·M W LightowlersB Abela-Ridder
Dec 26, 2012·Pathogens and Global Health·Robert H GilmanUNKNOWN Cysticercosis Working Group in Peru
Jun 20, 2014·Journal of Helminthology·A Tembo, P S Craig
Aug 8, 2013·PloS One·Lorenzo ZammarchiUNKNOWN COHEMI Project Study Group
Jun 16, 2016·The New England Journal of Medicine·Hector H GarciaUNKNOWN Cysticercosis Working Group in Peru
Jan 3, 2006·Parasitology International·Peter M Schantz
Jan 20, 2010·Trends in Parasitology·Nynke Deckers, Pierre Dorny
Apr 28, 2017·Tropical Medicine & International Health : TM & IH·Lorenzo ZammarchiUNKNOWN COHEMI Project Study Group
Apr 18, 2018·The American Journal of Tropical Medicine and Hygiene·Michelle Beam For The Cysticercosis Working Group In Peru
Mar 8, 2018·The Veterinary Record·Clare J PhythianEric R Morgan
Dec 19, 2018·The American Journal of Tropical Medicine and Hygiene·Andres G Lescano For The Cysticercosis Working Group In Peru
Sep 12, 2014·PLoS Neglected Tropical Diseases·Seth E O'NealUNKNOWN Cysticercosis Working Group in Peru
Jan 17, 2020·PLoS Neglected Tropical Diseases·Michelle M HabyMeritxell Donadeu
Jul 25, 2017·Current Opinion in Infectious Diseases·Camille Webb, Miguel M Cabada
Jul 17, 2020·PLoS Neglected Tropical Diseases·A Clinton WhiteHélène Carabin
Apr 11, 2018·Clinical Case Reports·Elchanan NussinsonFahmi Shibli
Jun 19, 2019·BMC Infectious Diseases·Xin-Zhong ZangShi-Zhu Li
Sep 22, 2018·Parasites & Vectors·Uffe Christian BraaeBrecht Devleesschauwer
May 31, 2018·Pharmaceuticals·Dorota OlenderLucjusz Zaprutko
May 29, 2020·Clinical Microbiology Reviews·Hector H GarciaRobert H Gilman
Mar 24, 2021·PLoS Neglected Tropical Diseases·Laura A SkripHélène Carabin
Aug 28, 2020·Journal of Molecular Graphics & Modelling·Ponciano García-GutiérrezAbraham Landa
May 8, 2021·Frontiers in Veterinary Science·Lucrecia Acosta SotoFernando Jorge Bornay-Llinares
May 28, 2021·Frontiers in Veterinary Science·Caitlin ButalaSusan Christina Welburn
Aug 12, 2021·Clinical Microbiology Reviews·Madeleine J RogersCatherine A Gordon
Aug 24, 2021·Emerging Infectious Diseases·Seth E O'NealUNKNOWN Cysticercosis Working Group in Peru

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Antiparasitics

Antiparasitics are medications which are indicated for the treatment of parasitic diseases. Discover the latest research on antiparasitics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.