Detection of the leukocyte group-5 antigens on normal and leukemic lymphocytes with the antibody-dependent cell-mediated cytotoxicity assay

Tissue Antigens
R P WarrenE D Thomas

Abstract

We have found that the antibody-dependent call-mediated cytotoxicity (ADCC) assay is capable of detecting the alleles of the group-5 antigenic system on peripheral blood lymphocytes. This finding should facilitate additional study of this system, as illustrated by the detection of group-5 antigens on leukemic cells, indicating that they are not lost from the cell surface upon malignant transformation.

References

Jul 1, 1964·Vox Sanguinis·A VAN LEEUWENJ J VAN ROOD

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Citations

Jan 1, 1984·Animal Blood Groups and Biochemical Genetics·D F Antczak
Mar 1, 1983·Tissue Antigens·A H Geurts van KesselA Hagemeijer

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