Detection of Tickborne Relapsing Fever Spirochete, Austin, Texas, USA

Emerging Infectious Diseases
Jack D BissettJob E Lopez

Abstract

In March 2017, a patient became febrile within 4 days after visiting a rustic conference center in Austin, Texas, USA, where Austin Public Health suspected an outbreak of tickborne relapsing fever a month earlier. Evaluation of a patient blood smear and molecular diagnostic assays identified Borrelia turicatae as the causative agent. We could not gain access to the property to collect ticks. Thus, we focused efforts at a nearby public park, <1 mile from the suspected exposure site. We trapped Ornithodoros turicata ticks from 2 locations in the park, and laboratory evaluation resulted in cultivation of 3 B. turicatae isolates. Multilocus sequencing of 3 chromosomal loci (flaB, rrs, and gyrB) indicated that the isolates were identical to those of B. turicatae 91E135 (a tick isolate) and BTE5EL (a human isolate). We identified the endemicity of O. turicata ticks and likely emergence of B. turicatae in this city.

References

Oct 23, 1997·International Journal of Systematic Bacteriology·A Le FlecheG Baranton
Sep 13, 2002·The American Journal of Tropical Medicine and Hygiene·Mark S DworkinDonald E Anderson
Jan 1, 1950·The American Journal of Tropical Medicine and Hygiene·R B EADS, H E HENDERSON
May 25, 2007·Veterinary Clinical Pathology·Marlyn S WhitneyMartin N Brillhart
Aug 30, 2008·Infectious Disease Clinics of North America·Mark S DworkinStephanie M Borchardt
Sep 27, 2013·PLoS Neglected Tropical Diseases·Job E LopezAndrea Varela-Stokes
Apr 5, 2014·PLoS Neglected Tropical Diseases·William K BoyleJob E Lopez
Jun 30, 2016·Journal of Veterinary Internal Medicine·J PiccioneM D Esteve-Gassent
Apr 19, 2017·Emerging Infectious Diseases·Anna M ChristensenBenjamin Stermole

❮ Previous
Next ❯

Citations

Feb 11, 2019·Transboundary and Emerging Diseases·Joseph J ModarelliMaria D Esteve-Gasent
Jul 28, 2020·Frontiers in Cellular and Infection Microbiology·Brittany A ArmstrongJob E Lopez
Jun 4, 2019·Zoonoses and Public Health·Stefanie B CampbellAlison Hinckley
Jun 2, 2020·Frontiers in Cellular and Infection Microbiology·Brittany A ArmstrongJob E Lopez
Jan 23, 2021·Scientific Reports·Adam J ReplogleJeannine M Petersen
Mar 5, 2021·Frontiers in Veterinary Science·Rachel E BusselmanGabriel L Hamer
Apr 30, 2021·Journal of Clinical Microbiology·Elizabeth A DietrichJeannine M Petersen
Sep 22, 2021·Emerging Infectious Diseases·Lisa EllisJob E Lopez
Nov 24, 2021·PLoS Neglected Tropical Diseases·Aparna KrishnavajhalaJob E Lopez

❮ Previous
Next ❯

Methods Mentioned

BETA
PCR
electrophoresis

Software Mentioned

Vector NTI
BLAST

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Annals of Tropical Medicine and Parasitology
Philippe ParolaDidier Raoult
PLoS Neglected Tropical Diseases
William K BoyleJob E Lopez
Emerging Infectious Diseases
Joshua ChristensenTom G Schwan
© 2022 Meta ULC. All rights reserved