Detector of 3-D salient points based on the dual-tree complex wavelet transform for the positioning of hippocampi meshes in magnetic resonance images.

Journal of Neuroscience Methods
Breno da Silveira SouzaRicardo J Ferrari

Abstract

Brain Magnetic Resonance (MR) image segmentation methods based on deformable models depend on the initial positioning to maximize the chances of successful segmentation. To minimize this limitation, salient-point based registration is used to perform the initial positioning of brain structure meshes close to their image target representation. The analysis of brain structures (such as the hippocampus) can help in the diagnosis and follow-up of neurodegenerative diseases like Alzheimer's. We present a technique for detection and description of 3-D salient points, which combines filter response maps estimated for different scales and orientations of the dual-tree complex wavelet transform (DT-CWT). We apply our technique to detect salient points in volumetric brain MR images and use the detected points in a positioning methodology. To illustrate the applicability, we applied our method for the positioning of hippocampi meshes in 3-D brain MR images and assessed the results by overlapping the positioned meshes with manual annotations made by medical specialists. Our method yielded mean values of normalized Dice Similarity Coefficient (nDSC) of 0.74/0.68 and Hausdorff Average Distance (HAD) of 0.73/0.75 for the left and right hippoc...Continue Reading

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