PMID: 9418237Jan 7, 1998Paper

Determinant role of E. coli RNase III in the decay of both specific and heterologous mRNAs

FEMS Microbiology Letters
J M SantosC M Arraiano

Abstract

A comparative analysis of mRNA decay was carried out in Escherichia coli using the wild-type and an isogenic RNase III deletion strain. We have studied the mRNA degradation from the Escherichia coli gene bolA, the Lactococcus lactis biovar diacetylactis citQRP operon and the Desulfovibrio vulgaris Hildenborough gene cyc. As seen by a dramatic stabilization of the specific mRNAs in the mutant strain, RNase III was crucial for the decay process of these three messages. Since RNase III, unlike RNase E, is not essential for bacterial viability we think that there is potential for using RNase III mutant strains to modulate gene expression.

References

Dec 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·J J Dunn, F W Studier
Oct 1, 1982·Cell·H D Robertson
Jan 1, 1996·Molecular Microbiology·D GoldenbergA B Oppenheim
Jul 1, 1993·World Journal of Microbiology & Biotechnology·C M Arraiano

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Citations

Oct 29, 2002·Biotechnology and Bioengineering·Christina D Smolke, Jay D Keasling
Sep 24, 2005·Journal of Molecular Microbiology and Biotechnology·Djamel Drider, Ciarán Condon
Jul 21, 2014·World Journal of Microbiology & Biotechnology·Inês Batista GuinoteCecília Maria Arraiano
Nov 6, 2007·Nucleic Acids Research·Sandra C ViegasCecília M Arraiano
Nov 17, 2009·Comptes rendus biologies·Flora PicardMuriel Cocaign-Bousquet
Aug 19, 2000·The Journal of Biological Chemistry·H WuS T Crooke
Mar 25, 2006·Molecular Microbiology·Jorge M SantosCecília M Arraiano
Jul 28, 2010·FEMS Microbiology Reviews·Cecília M ArraianoSandra C Viegas
Aug 28, 2021·Life·Alexandra PeregrinaCecília M Arraiano

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