Determinants for achieving the LDL-C target of lipid control for secondary prevention of cardiovascular events in Taiwan

PloS One
Li-Ting HoTaiwanese Secondary Prevention for patients with AtheRosCLErotic disease (T-SPARCLE) Registry Investigators

Abstract

Epidemiological and clinical studies have clearly established the link between low-density lipoprotein cholesterol (LDL-C) and atherosclerosis-related cardiovascular consequences. Although it has been a common practice for physicians to prescribe lipid-lowering therapy for patients with dyslipidemia, the achievement rate is still not satisfied in Taiwan. Therefore, the determinants for achieving the LDL-C target needed to be clarified for better healthcare of the patients with dyslipidemia. This registry-type prospective observational study enrolled the patients with cardiovascular diseases (coronary artery disease (CAD) and cerebrovascular disease (CVD)) from 18 medical centers across Taiwan, and clinically followed them for five years. At every clinical visit, vital signs, clinical endpoints, adverse events, concurrent medications and laboratory specimens were obtained as thoroughly as possible. The lipid profile (total cholesterol, high-density lipoprotein cholesterol, LDL-C, triglyceride), liver enzymes, and creatinine phosphokinase were evaluated at baseline, and every year thereafter. The cross sectional observational data was analyzed for this report. Among the 3,486 registered patients, 54% had their LDL-C < 100 mg/dL. ...Continue Reading

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Citations

Feb 16, 2017·European Journal of Preventive Cardiology·John MunkhaugenEinar Husebye
Mar 1, 2017·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Yi-Heng LiUNKNOWN Writing Group of 2017 Taiwan Lipid Guidelines for High Risk Patients
Apr 12, 2018·International Journal of Environmental Research and Public Health·Teppo RepoTiina Laatikainen
Jul 8, 2018·Journal of the Chinese Medical Association : JCMA·Yi-Heng LiMin-Ji Charng
Dec 16, 2020·Scientific Reports·Yi-Heng LiUNKNOWN Taiwanese Secondary Prevention for Patients with AtheRosCLErotic Disease (T-SPARCLE) Registry Investigators

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Methods Mentioned

BETA
coronary artery bypass
dissection

Software Mentioned

REALITY
SPSS
EUROASPIRE

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