PMID: 36846Apr 1, 1979

Determinants in microbial colonization of the murine gastrointestinal tract: pH, temperature, and energy-yielding metabolism of Torulopsis pintolopesii

Applied and Environmental Microbiology
J E Artwohl, D C Savage

Abstract

Torulopsis pintolopesii is an indigenous yeast that colonizes the secreting epithelia in the stomachs of mice and rats. A wild-type strain of this microbe was isolated and identified. To attempt to learn characteristics of the yeast that are advantageous to it in colonizing its natural habitat in vivo, we examined some aspects of its nutrition and energy-yielding metabolism and some environmental conditions that influence its growth in vitro. The yeast appeared to be limited in the compounds it can utilize as carbon and nitrogen sources. It grew best at 37 degrees C and did not grow at 23 or 43 degrees C. It grew optimally at neutral pH but could grow aerobically at pH values as low as 2.0 and anaerobically at pH values as low as 3.4. As assessed by measurements of growth rates and yield coefficients, it grew better aerobically than anaerobically. When grown aerobically, it had a cyanide-sensitive system for taking up O(2) and tested positively for cytochrome c oxidase activity. A petite mutant strain isolated from the wild-type strain had a growth rate and yield coefficient when incubated aerobically that were essentially the same as those of the wild-type parent grown anaerobically. Likewise similar to the wild-type parent gr...Continue Reading

Citations

Jul 1, 1990·Archiv für Tierernährung·M VanbelleM Focant
May 1, 2003·FEMS Microbiology Ecology·Jussi VaahtovuoErkki Eerola

Related Concepts

Candida utilis
Cytochrome c Oxidase Subunit VIa
Gastrointestinal System
Mesothelium
Fermentation
Hydrogen-Ion Concentration
Nitrogen
Oxygen Consumption
Carbohydrate Metabolism

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