PMID: 11311968Apr 20, 2001Paper

Determinants of albuminuria in people with Type 2 diabetes mellitus

Diabetes Research and Clinical Practice
L T PijlsJ T van Eijk

Abstract

This study sought to identify determinants of albuminuria in people with Type 2 diabetes. In 335 primary care patients, we assessed albumin-creatinine ratio (ACR) in two 24-h urine samples, and its cross-sectional associations with protein and alcohol intake, cigarette smoking, body weight and height, glycosuria, blood pressure, hypoglycaemic and antihypertensive treatment, gender, age, age at diagnosis, diabetes duration, family history of diabetes and cardiovascular diseases, ethnic origin, and education. The prevalence of micro- or macro-albuminuria (ACR> or =2.0 mg/mmol) was 33%. Among these patients, compared to those with normo-albuminuria, there were more men, protein intake (g/kg) estimated from urinary urea as well as systolic blood pressure and glycosuria were higher, there were more smokers, men were shorter, and a family history of diabetes was less prevalent (all P<0.05). In linear and logistic regression (n=270) albuminuria was independently associated (P<0.05 unless indicated otherwise) with systolic blood pressure (OR(10 mmHg)=1.32), smoking (OR(ex/never)=2.36, OR(current/never)=4.89), glycosuria (OR(> or =7/<1 g/l)=2.41), gender (OR(men/women)=2.50), age in men (OR(10 year)=1.60) (P<0.10) and, inversely, in wom...Continue Reading

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Citations

Nov 30, 2010·Journal of the American Dietetic Association·Marion J FranzErica Gradwell
Mar 18, 2003·Diabetes Research and Clinical Practice·Patrick J ManningShirley D Jones
Oct 2, 2003·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Geeta G GyamlaniTimothy S Larson
Feb 25, 2006·Journal of the Formosan Medical Association = Taiwan Yi Zhi·Tong-Yuan TaiUNKNOWN Diabcare (Taiwan) Study Group
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Aug 21, 2002·Current Opinion in Nephrology and Hypertension·Stephan R Orth, Eberhard Ritz

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