Determinants of Bowel Preparation Quality and Its Association With Adenoma Detection: A Prospective Colonoscopy Study

Medicine
Martin C S WongJoseph J Y Sung

Abstract

The predictors of poor bowel preparation in colorectal cancer screening participants have not been adequately studied, and the association between the quality of bowel preparation and adenoma detection has not been firmly established. This study examined the determinants of poor bowel preparation, and evaluated its relationship with adenoma detection.We included subjects aged between 50 and 70 years who received colonoscopy between 2008 and 2014 in a colorectal cancer screening program in Hong Kong. The quality of the bowel preparation was assessed by colonoscopists, and the factors associated with poor bowel cleansing were evaluated by a binary logistic regression analysis. A multivariate regression model was constructed to evaluate if poor bowel preparation was associated with detection of colorectal neoplasia.From 5470 screening participants (average age 57.7 years, SD 4.9), 1891 (34.6%) had poor or fair bowel preparation. The average cecal intubation time was 7.0 minutes (SD 5.4; range 1.22-36.9 minutes) and the average colonoscopy withdrawal time was 10.8 minutes (SD 6.9; range 6.0-107.0 minutes). Among all, 26.5% had colorectal neoplasia and 5.5% had advanced neoplasia. Older age (≥60 years; adjusted odds ratio [AOR] = 1....Continue Reading

References

Aug 1, 1996·Postgraduate Medicine·J D Tooson, L K Gates
Mar 10, 1999·Journal of the National Cancer Institute·J S MandelJ H Bond
Jun 23, 2001·The American Journal of Gastroenterology·R M NessN Chalasani
Jul 24, 2002·The American Journal of Gastroenterology·Douglas K RexL Lisa Bratcher
Jan 16, 2003·The American Journal of Gastroenterology·Devang N PrajapatiWalter J Hogan
Jul 3, 2003·Gastrointestinal Endoscopy·Gavin C HarewoodPat de Garmo
Mar 16, 2004·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Gavin C Harewood, David A Lieberman
Nov 1, 2005·The Lancet Oncology·Joseph J Y SungUNKNOWN Asia Pacific Working Group on Colorectal Cancer
Apr 26, 2006·The American Journal of Gastroenterology·Douglas K RexUNKNOWN ASGE/ACG Taskforce on Quality in Endoscopy
Jun 15, 2006·The American Journal of Gastroenterology·Dorte Ejg JarbolOve B Schaffalitzky de Muckadell
Dec 15, 2006·The New England Journal of Medicine·Robert L BarclayRoger L Greenlaw
Jul 22, 2008·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Robert L BarclayRoger L Greenlaw
May 14, 2010·The New England Journal of Medicine·Michal F KaminskiEugeniusz Butruk
Jan 5, 2011·Annals of Internal Medicine·Hermann BrennerMichael Hoffmeister
Dec 12, 2012·Gastrointestinal Endoscopy·Rodrigo JoverUNKNOWN COLONPREV study investigators
Jan 16, 2013·The American Journal of Gastroenterology·Philip O KatzRaymond E Joseph
Jan 22, 2013·CA: a Cancer Journal for Clinicians·Rebecca SiegelAhmedin Jemal
Mar 8, 2013·Endoscopy·S RodriguesG Macedo
Sep 21, 2013·The New England Journal of Medicine·Reiko NishiharaAndrew T Chan
Apr 4, 2014·The New England Journal of Medicine·Douglas A CorleyCharles P Quesenberry
Apr 22, 2014·American Journal of Preventive Medicine·Martin C S WongJoseph J Y Sung
Jun 18, 2014·The American Journal of Gastroenterology·Martin C S WongJoseph J Y Sung

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Citations

Dec 31, 2019·Frontline Gastroenterology·Ammar Al-RifaieMo Thoufeeq
Jul 7, 2017·European Journal of Gastroenterology & Hepatology·Joana Marques-AntunesPedro Pimentel-Nunes
Oct 14, 2018·Medicine·Seung-Joo NamChang Duck Kim
Jul 12, 2019·Journal of the Canadian Association of Gastroenterology·Valérie HeronAlan N Barkun
Mar 23, 2021·Annals of Surgical Treatment and Research·Rumi ShinWon-Kyung Kang
May 1, 2021·Cost Effectiveness and Resource Allocation : C/E·Jeffrey VoigtIan M Gralnek
Jul 6, 2021·Endoscopy International Open·Shimaa A AfifyMo H Thoufeeq

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