Determinants of concentric left ventricular hypertrophy in patients with resistant hypertension: RESIST-POL study

Hypertension Research : Official Journal of the Japanese Society of Hypertension
Piotr DobrowolskiPiotr Hoffman

Abstract

Left ventricular hypertrophy, especially concentric hypertrophy, has been shown to be an independent factor of cardiovascular diseases in patients with hypertension. Obstructive sleep apnea (OSA) and/or metabolic syndrome (MS) are common in patients with resistant hypertension (RHTN). The aim of this study was to evaluate factors associated with concentric hypertrophy in patients with RHTN. Data from 155 patients (92M, 63F) was analyzed. All patients underwent a thorough examination including: biochemical evaluations, ambulatory blood pressure monitoring, polysomnography and echocardiography. MS was defined by The Adult Treatment Panel III. Clinically significant OSA was defined as apnea/hypopnea index (AHI)>15 events per hour. Left ventricular mass index (LVMI) and relative wall thickness (RWT) were calculated. Four types of LV geometry were distinguished based on the LVMI and RWT. Patients were divided into four groups based on the LV geometric patterns: group 1 (normal geometry) (n=38, 24.4%); group 2 (concentric remodeling) (n=40, 25.8%); group 3 (eccentric hypertrophy) (n=26, 16.8%); and group 4 (concentric hypertrophy) (n=51, 33%). MS was found in 64% and OSA (AHI>15) in 43.2% of patients. Factors independently associated...Continue Reading

References

Jun 1, 1992·Journal of the American College of Cardiology·A GanauJ H Laragh
Jul 25, 2000·Circulation·B H Lorell, B A Carabello
Jun 5, 2003·Journal of Hypertension·UNKNOWN European Society of Hypertension-European Society of Cardiology Guidelines Committee
May 25, 2005·Journal of Internal Medicine·G MulèG Cerasola
Apr 23, 2010·Journal of Hypertension·Giovanni CioffiGiovanni de Simone
Jan 13, 2012·The Journal of Clinical Hypertension·Maria Czarina AcelajadoDavid A Calhoun
Mar 2, 2012·Circulation·Stacie L DaughertyP Michael Ho
Nov 13, 2012·European Heart Journal·Dharam J KumbhaniUNKNOWN REACH Registry Investigators
Apr 19, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Maria Lorenza MuiesanEnrico Agabiti Rosei
May 24, 2013·Journal of Human Hypertension·E FlorczakA Januszewicz
Sep 13, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Tetsuo NishikawaYoko Matsuzawa
May 9, 2014·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Gianfranco ParatiCarolina Lombardi

❮ Previous
Next ❯

Citations

Feb 19, 2016·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Anping CaiYingling Zhou
Nov 13, 2015·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Szu-Chia ChenHo-Ming Su
Oct 27, 2015·Current Hypertension Reports·Gabriela Querejeta Roca, Amil M Shah
Sep 22, 2016·World Journal of Nuclear Medicine·Semra OzdemirEmine Gazi
Jan 13, 2017·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Ayumi TanabeYutaka Imai
Jan 5, 2017·Circulation Journal : Official Journal of the Japanese Circulation Society·Lais Galvani de Barros CruzGuilherme Veiga Guimaraes
Oct 6, 2017·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Marcin WirtweinWojciech Sobiczewski

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.