Determinants of coronary flow abnormalities in obstructive type hypertrophic cardiomyopathy: noninvasive assessment by transthoracic Doppler echocardiography

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Seden CelikTuna Tezel

Abstract

We aimed to visualize the coronary flow velocities (CFV) of patients with hypertrophic obstructive cardiomyopathy by using transthoracic Doppler echocardiography, and to determine the relationship between abnormal CFV patterns and conventional echocardiography indices. Guided by 2-dimensional echocardiography and Doppler color flow mapping, CFV in the distal left anterior descending coronary artery were measured in 21 patients with hypertrophic obstructive cardiomyopathy using a 3.5-MHz transducer. The results were compared with those of 18 control subjects. Abnormal systolic flow patterns were observed in 15 (71%) patients (11 systolic-reversal flow and 4 no systolic flow). For patients and control subjects, peak diastolic velocity and velocity-time integral obtained from distal left anterior descending coronary artery were higher (63 +/- 21 cm/s and 18.5 +/- 4 cm vs 41 +/- 11 cm/s and 14.2 +/- 5 cm, respectively; P <.01 for both) whereas peak systolic velocity and velocity-time integral were significantly lower (-17 +/- 10 cm/s and 4.5 +/- 6 cm vs 24 +/- 9 cm/s and 9.5 +/- 4 cm, respectively; P <.001 for both). Significant positive and negative correlations between diastolic CFV and septal thickness index (r = 0.79, P <.0001)...Continue Reading

References

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Citations

May 7, 2013·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Milorad TesicBosiljka Vujisic-Tesic
Dec 27, 2005·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Cesare de Gregorio
Dec 15, 2016·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Claire E RaphaelSanjay K Prasad
Feb 26, 2008·European Journal of Echocardiography : the Journal of the Working Group on Echocardiography of the European Society of Cardiology·Patrick Meimoun, Christophe Tribouilloy
Oct 1, 2009·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·C CamaroH A Bosker

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