PMID: 3383654Jul 1, 1988Paper

Determinants of daytime sleepiness in obstructive sleep apnea

Chest
C GuilleminaultG Nino-Murcia

Abstract

To investigate determinants of daytime sleepiness in obstructive sleep apnea syndrome (OSAS), we studied 100 unselected OSAS patients by nocturnal polygraphic recording and the Multiple Sleep Latency Test (MSLT). Data obtained were submitted to three types of analysis. Respiratory disturbance index, oxygen saturation indices, body mass index, and total nocturnal sleep time did not significantly correlate with daytime sleepiness, as measured by the MSLT. Analysis of subgroups based on weight and degree of alertness also showed a nonsignificant correlation with daytime sleepiness. The best predictor of the excessive daytime sleepiness (EDS) frequently found in OSAS patients was the nocturnal polygraphic recording of the sleep disturbances and sleep structure anomalies that reflect the brain's overall dysfunction in OSAS. Understanding why an electroencephalogram arousal response occurs during sleep in association with abnormal breathing and how this response can become blunted may help us to better predict the development of EDS.

References

Jul 1, 1967·British Journal of Preventive & Social Medicine·T Khosla, C R Lowe
Jan 1, 1982·Neurobiology of Aging·M A CarskadonW C Dement

❮ Previous
Next ❯

Citations

Jan 1, 1995·International Journal of Clinical Monitoring and Computing·T JokinenM Partinen
Feb 23, 2010·Sleep & Breathing = Schlaf & Atmung·Athanasios G XiromeritisNikiforos V Angelopoulos
Apr 6, 2011·Sleep & Breathing = Schlaf & Atmung·Yuanfeng SunXiangdong Tang
Jan 19, 2012·Sleep & Breathing = Schlaf & Atmung·Shyam SubramanianSalim Surani
Jan 24, 2013·Sleep & Breathing = Schlaf & Atmung·Jorge Rey de Castro, Edmundo Rosales-Mayor
Sep 1, 1995·Electroencephalography and Clinical Neurophysiology·R D ChervinC Guilleminault
Jul 1, 1992·Computer Methods and Programs in Biomedicine·S C KirbyR B George
Oct 3, 2006·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Kenny P PangRobert Podolsky
Jun 7, 2005·Primary Care·Mark E Dyken, Thoru Yamada
Jul 20, 2002·Journal of Psychosomatic Research·Donald L Bliwise
Aug 18, 2004·Sleep Medicine Reviews·R J DaviesJ R Stradling
Aug 18, 2004·Sleep Medicine Reviews·H Engleman, D Joffe
Jul 1, 1996·Journal of the International Neuropsychological Society : JINS·E VerstraetenJ De Roeck
Nov 1, 1991·Journal of Clinical and Experimental Neuropsychology·M A BédardJ Malo
Oct 3, 2002·The Journal of Cardiovascular Nursing·Kathy C RichardsCorey L Nagel
May 23, 2008·Critical Care Medicine·Belen CabelloLaurent Brochard
Aug 1, 1996·Thorax·R J Davies, J R Stradling
Sep 10, 1998·American Journal of Respiratory and Critical Care Medicine·L S BennettR J Davies
Jan 5, 1999·American Journal of Respiratory and Critical Care Medicine·J R StradlingR J Davies
Jun 3, 1999·American Journal of Respiratory and Critical Care Medicine·N M PunjabiK Bandeen-Roche
May 12, 2000·American Journal of Respiratory and Critical Care Medicine
Aug 10, 2000·American Journal of Respiratory and Critical Care Medicine·J E BlackO Carrillo
Mar 19, 2002·American Journal of Respiratory and Critical Care Medicine·Maree BarnesRobert J Pierce
Mar 1, 1990·The American Review of Respiratory Disease·S W WesmillerJ H Dauber
Jun 1, 1992·The American Review of Respiratory Disease·F SérièsY Cormier
Nov 1, 1992·The American Review of Respiratory Disease·F SérièsG Carrier
Oct 31, 2002·American Journal of Respiratory and Critical Care Medicine·Sairam Parthasarathy, Martin J Tobin
Dec 14, 2004·American Journal of Respiratory and Critical Care Medicine·Ronald D ChervinDeborah L Ruzicka
Sep 1, 2011·Clinical Nursing Research·Barbara RiegelLee R Goldberg
Jan 9, 2010·Journal of the American Statistical Association·Ciprian M CrainiceanuNaresh M Punjabi
Jan 1, 2011·Journal of the American Statistical Association·Ciprian M CrainiceanuNaresh M Punjabi
Oct 16, 2013·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Kim L WardSutapa Mukherjee
Jan 18, 2014·American Journal of Hypertension·Yu-Jin G Lee, Do-Un Jeong
Jan 1, 1997·Journal of the American Academy of Child and Adolescent Psychiatry·T F Anders, L A Eiben
Feb 15, 2002·Journal of the American Geriatrics Society·M Cohen-ZionS Ancoli-Israel
Dec 18, 2013·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Kimberly A BabsonSteven H Woodward
Mar 11, 1998·Journal of Sleep Research·S E MartinN J Douglas
Jun 7, 2005·Primary Care·Syed W Malik, Joseph Kaplan
Jan 2, 2007·Current Opinion in Critical Care·Belen CabelloJordi Mancebo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.