Determinants of heart rate variability in chronic hemodialysis patients

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
K TamuraT Iwasaka

Abstract

To clarify determinants of heart rate variability in hemodialysis patients, we evaluated 187 patients receiving chronic hemodialysis. Ambulatory electrocardiogram was recorded for 24 hours from the beginning of hemodialysis. Standard deviation of the normal RR interval (SDNN) was used as a marker of heart rate variability. Multiple regression analysis was performed to select independent variables associated with SDNN from the following 14 variables: age, sex, body mass index before hemodialysis, presence of ischemic heart disease, diabetic nephropathy as primary renal disease, smoking, duration of hemodialysis, mean blood pressure before hemodialysis, left ventricular mass index and fraction shortening in echocardiography, use of beta blockers, use of angiotensin-converting enzyme inhibitors, hematocrit, and blood urea nitrogen. Older age (P < 0.0001), presence of diabetic nephropathy as primary renal disease (P < 0.0001), lower hematocrit (P = 0.0121), larger body mass index before hemodialysis (P = 0.0133), longer duration of hemodialysis (P = 0.0200), and smoking (P = 0.0350) were associated with reduced SDNN. In hemodialysis patients, SDNN as a marker of cardiac autonomic modulation was associated with hematocrit, body mass...Continue Reading

Citations

Jan 18, 2008·International Journal of Cardiology·Keiko OikawaHaruki Itoh
Jan 1, 2010·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Rodica Pop-BusuiEva L Feldman
Mar 15, 2011·Hemodialysis International·Atac CelikAlaettin Avsar
Nov 5, 2008·Annales de cardiologie et d'angéiologie·E SalamehG Badaoui
Jun 24, 2006·Annales de cardiologie et d'angéiologie·Elie Salame, Roland Kassab
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Aug 9, 2006·The American Journal of Cardiology·Ilan GoldenbergUNKNOWN Multicenter Automatic Defibrillator Implantation Trial-II Investigators
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Jun 21, 2012·Hemodialysis International·Konstantina TrigkaChristopher T Chan
Mar 18, 2017·BMC Nephrology·Jiun-Chi HuangHung-Chun Chen
Nov 10, 2000·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·M Schömig, E Ritz

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