PMID: 2502951Jun 1, 1989Paper

Determinants of homologous blood usage utilizing autologous platelet-rich plasma in cardiac operations

The Annals of Thoracic Surgery
G F GiordanoB S Strug

Abstract

The present study evaluated (1) the influence of the collection of autologous platelet-rich plasma intraoperatively in addition to intraoperative autotransfusion on homologous blood usage and bleeding in cardiac operations; (2) the influence of age, sex, body surface area, type of operation, and reoperations on homologous blood usage and bleeding in cardiac operations utilizing intraoperative autotransfusion and autologous platelet-rich plasma collected intraoperatively; and (3) the influence of the preoperative administration of aspirin, Persantine (dipyridamole), heparin sodium, thrombolytic agents, Coumadin (crystalline warfarin sodium), and nonsteroid, antiinflammatory drugs on homologous blood usage and bleeding in cardiac operations utilizing intraoperative autotransfusion and autologous platelet-rich plasma collected intraoperatively. The results demonstrated a decrease in homologous blood use and bleeding when autologous platelet-rich plasma is collected in addition to the use of intraoperative autotransfusion. All of the patient and procedural variables influenced homologous blood usage and bleeding to some extent. Only the thrombolytic agents affected blood usage by increasing homologous plasma usage. All other drugs ...Continue Reading

References

Nov 11, 1988·JAMA : the Journal of the American Medical Association
Jan 1, 1988·The Annals of Thoracic Surgery·V A FerrarisW R Berry
Mar 1, 1987·The Annals of Thoracic Surgery·S V KarwandeV A Subramanian
Feb 1, 1985·Mayo Clinic Proceedings·M A PopovskyH F Taswell

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Citations

Sep 1, 1993·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·S K BoeyS S Dhara
Jul 2, 1999·The American Journal of Medicine·A I Schafer
Mar 2, 1999·British Journal of Haematology·D H Bevan
Dec 9, 2004·Transfusion·Paul S Potter
Sep 1, 1990·Journal of Cardiac Surgery·J R Utley
Jun 20, 2002·Journal of Cardiothoracic and Vascular Anesthesia·S M S FordT Treasure
Apr 1, 1991·The Annals of Thoracic Surgery·J W JonesJ I Thornby
Apr 1, 1990·The Annals of Thoracic Surgery·J W JonesD A Lindsley
Feb 1, 1993·Journal of Cardiothoracic and Vascular Anesthesia·G P Gravlee
Nov 1, 1996·The Annals of Thoracic Surgery·J T ChristensonM Schmuziger
Sep 1, 1993·The Annals of Thoracic Surgery·V A FerrarisR R Klingman
Aug 1, 1990·American Journal of Surgery·R L TawesE J Harris
Dec 1, 1996·Anesthesia and Analgesia·K J TumanA D Ivankovich
Aug 1, 1995·Anesthesia and Analgesia·L Shore-LessersonG Silvay
Feb 25, 2020·PloS One·Steven Walczak, Vic Velanovich

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