Determinants of nosocomial infection in 6 neonatal intensive care units: an Italian multicenter prospective cohort study

Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America
Cinzia AuritiVincenzo Di Ciommo

Abstract

Nosocomial infections are still a major cause of morbidity and mortality among neonates admitted to neonatal intensive care units (NICUs). To describe the epidemiology of nosocomial infections in NICUs and to assess the risk of nosocomial infection related to the therapeutic procedures performed and to the clinical characteristics of the neonates at birth and at admission to the NICU, taking into account the time between the exposure and the onset of infection. A multicenter, prospective cohort study. A total of 1,692 neonates admitted to 6 NICUs in Italy were observed and monitored for the development of nosocomial infection during their hospital stay. Data were collected on the clinical characteristics of the neonates admitted to the NICUs, their therapeutic interventions and treatments, their infections, and their mortality rate. The cumulative probability of having at least 1 infection and the cumulative probability of having at least 1 infection or dying were estimated. The hazard ratio (HR) for the first infection and the HR for the first infection or death were also estimated. A total of 255 episodes of nosocomial infection were diagnosed in 217 neonates, yielding an incidence density of 6.9 episodes per 1,000 patient-da...Continue Reading

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Citations

Jul 14, 2012·Indian Pediatrics·Fatih BolatAsiye Nuhoglu
Feb 28, 2013·International Journal of Environmental Research and Public Health·Giuliana FabbriPatrizia Farruggia
Dec 4, 2012·Nutrients·Walter ZinggMaria Martin
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Oct 12, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Ana C BlanchardCaroline Quach
Apr 28, 2016·European Journal of Pediatrics·Evelien Hilde VerstraeteStijn Blot
Mar 5, 2017·Italian Journal of Pediatrics·Carmine GarzilloRaffaele Zarrilli
Aug 1, 2013·The Pediatric Infectious Disease Journal·Ming-Horng TsaiYhu-Chering Huang
Feb 14, 2014·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Sorabh DharKeith S Kaye
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May 30, 2021·Early Human Development·Ralciane P MenezesDenise V D B Röder

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