Determinants of persistent organic pollutant (POP) concentrations in human breast milk of a cross-sectional sample of primiparous mothers in Belgium

Environment International
Raf AertsAdrian Covaci

Abstract

Bio-accumulation of persistent organic pollutants (POPs) in the environment and in the food chain can lead to high pollutant concentrations in human fat-containing tissues and breast milk. We aimed to identify the maternal characteristics that determined POP concentrations in breast milk of primiparous mothers in Belgium. Breast milk samples were obtained from a cross-sectional sample of 206 primiparous mothers in 2014. POP concentrations in breast milk samples were determined by GC-ECNI-MS and GC-EI-MS/MS depending on the analytes' sensitivity. Associations between POP concentrations in breast milk and potential determinants were investigated using two-way contingency tables and multivariable generalized linear models. Fifteen of the 23 screened POPs were detected in the breast milk samples. Four organochlorine compounds (p,p'-DDT, p,p'-DDE, HCB and β-HCH) and two brominated flame retardant congeners (BDE-47, BDE-153) were detected at concentrations above the limit of quantification in >50% of the breast milk samples. Maternal age and BMI were usually associated with higher POP concentrations. Rural residency and consumption of home-produced eggs, fatty fish and fish oil supplements were associated with higher concentrations o...Continue Reading

Citations

May 22, 2020·The Science of the Total Environment·Ana Pérez de VargasRafael Mateo
Feb 6, 2021·Biological Trace Element Research·Iman Al-Saleh
Jan 13, 2021·Seminars in Perinatology·Sharon PerrellaDonna Geddes
Jun 9, 2021·Environmental Science and Pollution Research International·Mahesan Naidu SubramaniamAhmad Fauzi Ismail
Jun 4, 2021·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Giulia PomaAdrian Covaci

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