PMID: 489016Sep 1, 1979Paper

Determinants of plasma uric acid

Human Genetics
C L GulbrandsenA Kagan

Abstract

Obesity, alcohol consumption, and hematocrit provide an index of plasma uric acid, which in path analysis has a cultural heritability of 0.11 in children and 0.23 in parents, a small maternal effect, and a genetic heritability of 0.25 in both generations. Preliminary evidence for a major locus is destroyed by the omission of one exceptional child. There is no evidence against the polygenic hypothesis for hyperuricemia in the Japanese-American population studied.

Associated Clinical Trials

References

May 1, 1979·Annals of Human Genetics·D C RaoS Yee
Jan 1, 1979·American Journal of Medical Genetics·N E Morton
Jan 1, 1969·Journal of Chronic Diseases·R M Acheson, Y K Chan
Oct 1, 1949·Annals of Internal Medicine·R M STECHERW M SOLOMON
Nov 1, 1948·The Journal of Clinical Investigation·C J SmythR H Freyberg
Dec 1, 1975·International Journal of Epidemiology·A KaganJ C Schiffman

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Citations

May 1, 1988·Human Genetics·Y FriedlanderY Stein
May 1, 1980·Behavior Genetics·F M AhernG C Ashton
Jun 1, 1996·Journal of Clinical Epidemiology·C IribarrenK Yano
Mar 21, 2012·Journal of the American Geriatrics Society·Jennifer Yi-Chun LaiMarkus Bitzer
Aug 1, 1984·International Journal of Cardiology·H B Hubert
Jan 1, 1980·Human Genetics·H KriegerE Azevêdo
Sep 1, 1980·Jinrui idengaku zasshi. The Japanese journal of human genetics·K S ParkA Asaka
Sep 1, 1983·American Journal of Physical Anthropology·D C RaoJ M Russell
Apr 1, 1979·Genetical Research·D C RaoC R Cloninger
May 8, 2000·American Journal of Medical Genetics·D R Reed, R A Price
Jan 1, 1984·Acta geneticae medicae et gemellologiae·E InouyeA Asaka

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