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Determinants of platelet number and regulation of thrombopoiesis

Hematology

Dec 17, 2009

K Kaushansky

Abstract

Our understanding of thrombopoiesis has improved greatly in the last two decades with the availability of in vitro assays of megakaryocyte progenitor cell growth, with the cloning and characterization of stem cell factor (SCF) and thrombopoietin (Tpo), the latter the primary humoral reg...read more

Mentioned in this Paper

Thrombocytopenia
Megakaryocytes
Murine
Thrombopoiesis
Thrombopoietin Receptor
Biologic Development
Renal Insufficiency
Stem Cell Factor Binding
Cytokine
THPO gene
Paper Details
References
  • References28
  • Citations44
123
  • References28
  • Citations44
12345

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Determinants of platelet number and regulation of thrombopoiesis

Hematology

Dec 17, 2009

K Kaushansky

PMID: 20008193

DOI: 10.1182/asheducation-2009.1.147

Abstract

Our understanding of thrombopoiesis has improved greatly in the last two decades with the availability of in vitro assays of megakaryocyte progenitor cell growth, with the cloning and characterization of stem cell factor (SCF) and thrombopoietin (Tpo), the latter the primary humoral reg...read more

Mentioned in this Paper

Thrombocytopenia
Megakaryocytes
Murine
Thrombopoiesis
Thrombopoietin Receptor
Biologic Development
Renal Insufficiency
Stem Cell Factor Binding
Cytokine
THPO gene

Similar Papers Found In These Feeds

Hematopoietic Stem Cells (Keystone)

Hematopoietic stem cells (HSCs) are the cells that give rise to blood cells of the myeloid and lymphoid lineage during hematopoiesis. Follow this feed to learn more about hematopoietic stem cells and related research.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

Related Papers

Seminars in Hematology

Apoptotic processes in megakaryocytes and platelets

Seminars in HematologyJuly 14, 2010
Michael J White, Benjamin T Kile
American Journal of Physiology. Endocrinology and Metabolism

Adipokines oversecreted by omental adipose tissue in human obesity

American Journal of Physiology. Endocrinology and MetabolismJune 21, 2007
E MauryS M Brichard
Paper Details
References
  • References28
  • Citations44
123
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