Determinants of quality of life in irritable bowel syndrome

Journal of Clinical Gastroenterology
Enrique ReyManuel Diaz-Rubio

Abstract

Health-related quality of life (HRQOL) is a main outcome in irritable bowel syndrome (IBS), but most studies have been conducted on moderate-severe patients. We sought to ascertain the relative contribution of severity, anxiety, and personality to impairment of HRQOL in a sample representative of the entire IBS spectrum. IBS consulters, IBS nonconsulters, and controls were invited to complete questionnaires designed to measure severity of IBS (Functional Bowel Disease Severity Index), anxiety (State-trait Anxiety Inventory), personality (Minnesota Multiphasic Personality Inventory-2), and HRQOL [Short Form 36 (SF-36)]. The SF-36 scores of the study groups were compared, and a multiple regression model was constructed. Sixty-six IBS consulters, 70 nonconsulters, and 117 controls were studied. All 3 groups differed in terms of SF-36 physical (46.5+/-9.4 vs. 50.5+/-8.0 vs. 54.5+/-6.0) and mental composite scores (38.2+/-12.5 vs. 43.2+/-12.0 vs. 46.7+/-10.6). Although physical scores were linked to hypochondriasis (beta=-0.39; P<0.001), severity of pain (beta=-0.28; P<0.001), and age, mental scores were associated with state anxiety (beta=-0.36; P<0.001) and trait anxiety (beta=-0.40; P<0.001). HRQOL is impaired in all subgroups of...Continue Reading

References

Jun 15, 1992·Annals of Internal Medicine·D A Drossman, W G Thompson
Jul 1, 1995·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·E A O'KeefeS J Jacobsen
Nov 1, 1996·Digestive Diseases and Sciences·W E WhiteheadE Taub
Dec 14, 1999·Alimentary Pharmacology & Therapeutics·O Y LeeL Chang
Dec 22, 1999·Journal of Clinical Gastroenterology·M W RussoD A Drossman
Jan 19, 2000·The American Journal of Gastroenterology·N A KoloskiP M Boyce
Apr 14, 2000·The American Journal of Gastroenterology·D A DrossmanH Jia
Sep 13, 2000·Gastroenterology·I M GralnekE A Mayer
May 29, 2002·Alimentary Pharmacology & Therapeutics·H B El-SeragD Bjorkman
Jun 25, 2002·Journal of Clinical Gastroenterology·Rosalie P PatelBarbara J Zarowitz
Aug 31, 2002·PharmacoEconomics·Xavier BadiaNicholas J Talley
Nov 12, 2002·The American Journal of Gastroenterology·UNKNOWN American College of Gastroenterology Functional Gastrointestinal Disorders Task Froce
Mar 19, 2003·Alimentary Pharmacology & Therapeutics·A P S HunginF Mearin
Mar 26, 2003·The American Journal of Gastroenterology·George F LongstrethJoshua J Ofman
Jul 29, 2003·Psychosomatic Medicine·Peter HenningsenHeribert Sattel
Mar 26, 2004·Gastroentérologie Clinique Et Biologique·Benoit CoffinFrançois Dyard
Apr 20, 2004·Journal of Psychosomatic Research·Francis Creed, Arthur Barsky
Sep 15, 2004·Archives of Internal Medicine·Brennan M R SpiegelBruce Naliboff
Sep 15, 2004·Journal of Clinical Gastroenterology·Ian M GralnekEmeran A Mayer
Oct 20, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Anthony LemboDouglas A Drossman
Jan 13, 2006·The American Journal of Gastroenterology·Kevin C CainMargaret M Heitkemper
Mar 28, 2006·Gastroentérologie Clinique Et Biologique·Michel AmourettiAbdelkader El Hasnaoui

❮ Previous
Next ❯

Citations

Jul 3, 2010·Journal of Gastroenterology and Hepatology·Kok-Ann GweeUNKNOWN Asian Neurogastroenterology and Motility Association
Sep 22, 2010·World Journal of Gastroenterology : WJG·Erja MalinenAiri Palva
Apr 30, 2011·World Journal of Gastroenterology : WJG·Bartosz FiderkiewiczAndrzej Rydzewski
Nov 24, 2011·World Journal of Gastroenterology : WJG·P Patrick BasuTommy Pacana
Feb 6, 2010·The American Journal of Tropical Medicine and Hygiene·Herbert L DuPontZhi-Dong Jiang
Aug 4, 2010·Journal of Neurogastroenterology and Motility·Moo In Park
Aug 4, 2010·Journal of Neurogastroenterology and Motility·Dong Won Park, Oh Young Lee
Mar 29, 2014·Current Medical Research and Opinion·Brooks D Cash
Jul 4, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·R L BurrM M Heitkemper
Oct 16, 2015·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·C GrinsvallM Simrén
Aug 1, 2015·Health and Quality of Life Outcomes·Vilde Lehne MichalsenPer G Farup
Feb 11, 2015·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Véronique De Gucht
Feb 26, 2011·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Joong Goo KwonUNKNOWN Korean Society of Neurogastroenterology and Motility
Oct 29, 2018·Digestive Diseases and Sciences·Moritz von WulffenGerald Holtmann
May 9, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Claudio B S OliveiraValter F Andrade-Neto
Jul 8, 2014·European Journal of Gastroenterology & Hepatology·Ae Lee JangDong Uk Kim
Jul 27, 2017·BioMed Research International·Sanda Pletikosić Tončić, Mladenka Tkalčić
Feb 16, 2019·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Sverre LitleskareKnut-Arne Wensaas
Jun 4, 2020·Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates·Gillian E CassarDavid W Austin
Sep 21, 2016·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Yong Hwan Kwon, Hyun Jin Kim
Jul 18, 2020·Journal of Neurogastroenterology and Motility·Jia LuXiucai Fang

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

© 2022 Meta ULC. All rights reserved