Determinants of tidal volumes with adaptive support ventilation: a multicenter observational study

Anesthesia and Analgesia
Dave A DongelmansMarcus J Schultz

Abstract

In the present study, we investigated the behavior of adaptive support ventilation (ASV) in patients after cardiothoracic surgery. We determined tidal volumes (Vt) and factors that influence Vt with this mode of microprocessor-controlled mechanical ventilation (MV). This was a prospective, multicenter, observational study in three Dutch intensive care units over a 5-mo period. MV data were collected during steady-state after arrival in the intensive care unit. Data were collected for 346 consecutive patients after cardiothoracic surgery: 262 patients weaned with ASV, and 84 patients weaned with pressure-controlled/pressure-support MV. With ASV the mean (+/- sd) Vt expressed per kilogram actual body weight was 7.1 +/- 1.6 mL. Expressed per kilogram ideal body weight (IBW), Vt was 8.3 +/- 1.5 mL. In patients with a correctly set body weight (SBW) (i.e., the IBW), Vt was 8.1 +/- 1.4 mL/kg. With pressure-controlled/pressure-support-MV Vt was 7.3 +/- 1.4 mL/kg IBW (P < 0.001 vs ASV). Multivariate logistic regression analysis showed Vt with ASV to be dependent on only two parameters: respiratory rate and the correctness of SBW. Vt with ASV seems to be dependent on two parameters: respiratory rate and the correctness of SBW. The first...Continue Reading

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Citations

Jan 23, 2013·Intensive Care Medicine·François LelloucheMarc Wysocki
Dec 4, 2009·Current Opinion in Critical Care·Giorgio Conti, Roberta Costa
Dec 14, 2011·Critical Care Nursing Quarterly·Carl F Haas, Kimberly A Bauser
Nov 27, 2019·International Journal of Molecular Sciences·Yu-Ling DaiKun-Lun Huang
Aug 12, 2020·Intensive Care Medicine·Annemijn H JonkmanLaurent J Brochard
Aug 24, 2018·Intensive Care Medicine Experimental·Matthias van der Staay, Robert L Chatburn

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