PMID: 11912297Mar 26, 2002Paper

Determinants of uraemic toxin removal

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
W R Clark, Dayong Gao

Abstract

The inability to excrete a wide spectrum of toxins is one of the hallmarks of uraemia and is responsible for many of the signs and symptoms of this syndrome. Therefore, an understanding of the factors influencing uraemic toxin removal, during both the pre-dialysis and dialytic phases, is critically important. This review addresses many of these factors, which include the importance of preserved residual renal function and the effect of therapy frequency. In addition, specifically with respect to larger uraemic toxins, the importance of convection and treatment duration is discussed. All of these issues will be major considerations as new dialytic therapies for end-stage renal disease patients are developed and implemented.

Citations

Jan 25, 2005·Seminars in Dialysis·Zhongping HuangDayong Gao
Dec 7, 2011·Hemodialysis International·Andrew Davenport
Mar 14, 2013·Hemodialysis International·Sivakumar SridharanKen Farrington
Mar 19, 2009·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Anil Chandra AttaluriWojciech Misiolek

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