PMID: 9192970May 1, 1997Paper

Determination of 3D dose distribution from intracavitary brachytherapy of cervical cancer by MRI of irradiated ferrous sulphate gel

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
B H KnutsenD R Olsen

Abstract

MRI ferrous sulphate gel dosimetry has proven to be a valuable method for assessment of dose delivered in teletherapy. The intention of this study was to investigate ferrous sulphate gel as a possible dosimeter for intracavitary brachytherapy applications. A plastic duplicate of a cervix ring applicator set was submerged in Fe2(+)-infused gelatin gel. The gel was subsequently irradiated by a stepwise moving 192Ir source, using automatic afterloading equipment (Microselectron, Nucletron-Oldelft International BV, Veenendaal, The Netherlands). A 3D dose distribution was reconstructed from MR images of the gel. The gel dose measurements were found to be of the same accuracy as TLD measurements. Isodose curves based on gel dosimetry and isodose curves computed by a dose planning system were generally less than 2 mm apart. MR images showing the position of the applicator set in a patient during treatment were used to obtain images describing patient anatomy in the sagittal and ring planes of the applicator set. Isodose curves computed from the gel measurements were then superimposed on these images, illustrating one possible way of linking dosimetrical and anatomical data. Our study shows that MRI ferrous sulphate gel dosimetry is a ...Continue Reading

References

Jul 1, 1992·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·K S KappA G Hackl
Dec 1, 1990·Physics in Medicine and Biology·M J Day
Dec 1, 1990·Physics in Medicine and Biology·R J SchulzJ C Gore
Oct 1, 1988·Physics in Medicine and Biology·A S MeigooniR Nath
Jan 1, 1988·Gynecologic Oncology·J A StrykerJ Shafer
Dec 1, 1987·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·R S ColtartA K Dixon
Oct 1, 1984·Physics in Medicine and Biology·J C GoreR J Schulz

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Citations

Apr 6, 2004·Brachytherapy·Beth A Erickson
Oct 24, 2001·Magnetic Resonance Imaging·C MaldjianR Adam
May 16, 2007·Medical Physics·C AusterlitzC Sibata
Jan 22, 2000·Radiology·A R Margulis, J H Sunshine
Jan 30, 1999·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Y De DeeneE Achten
Jul 31, 2002·Zeitschrift für medizinische Physik·Yves De Deene
Sep 5, 2006·NMR in Biomedicine·Cecilie BrekkeMichel Modo
Dec 24, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Thomas M PisanskyHoward M Sandler
Oct 26, 1999·Physics in Medicine and Biology·E PappasL Vlachos
Dec 22, 1998·Acta Oncologica·D R Olsen, O S Bruland
Nov 27, 2001·Physics in Medicine and Biology·Y De DeeneC De Wagter

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