Determination of 3D PSFs from computed tomography reconstructed x-ray images of spherical objects and the effects of sphere radii

Medical Physics
Normand RobertCari Whyne

Abstract

A method was developed to obtain three-dimensional (3D) point spread functions (PSFs) of reconstructed x-ray volumetric images using spheres of known diameters. The algorithm consists of a sphere localization step using template matching applied to the entire volume. Richardson Lucy (RL) deconvolution is used atypically to determine the PSF from the reconstructed x-ray image and a model of the sphere. The resulting PSF is arbitrary, that is, there are no assumptions of separability or symmetry. Oversampling is not used, and sample spacing matches the image. The effect of sphere radius on PSF estimate reproducibility is investigated. Phantoms were constructed by suspending five polytetrafluoroethylene (PTFE) spheres having known radii equal to 4.77, 7.95, 9.52, 12.68, and 19.53 mm in an agar solution. The phantom included a 25 μm steel wire to calculate a line spread function (LSF). The phantom was imaged and reconstructed with a Medtronic surgical O-Arm 23 times and a Toshiba Aquilion One computed tomography (CT) 20 times. A sharp reconstruction kernel exhibiting a nonmonotonic PSF was used with the Toshiba CT. PSFs and LSFs were computed for all of the images and repeated estimates were used to compute mean and standard deviat...Continue Reading

References

Jan 1, 1988·Physics in Medicine and Biology·E L Nickoloff
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Jul 10, 2013·Journal of Applied Clinical Medical Physics·Akihiro KayugawaShinichi Wada
Jan 7, 2014·Medical Physics·Amirreza PakdelCari M Whyne

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Citations

Mar 19, 2020·Medical Physics·Changwoo LeeJongduk Baek

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