Determination of acrylamide in food using a UPLC-MS/MS method: results of the official control and dietary exposure assessment in Cyprus

Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Demetris KafourisStelios Yiannopoulos

Abstract

The determination of acrylamide in potato products, bakery products and coffee, and the human dietary exposure is reported. The method reported is based on a single extraction step with water, followed by the clean-up of the extract using solid phase extraction columns and finally, the determination of acrylamide using UPLC-MS/MS. The MS/MS detection was carried out using an ESI interface in positive ion mode. Internal calibration was used for the quantification of acrylamide, because of the suppression/enhancement matrix effects due to the complex nature of the samples. The method performance characteristics were determined after spiking blank samples. The mean recoveries in spiked coffee samples, potato chips, breakfast cereals and crispbread ranged from 93% to 99%, with RSDs lower than 5% for both repeatability and reproducibility conditions. The estimated limits of detection and quantification of the method were 10 and 32 μg kg-1, respectively. The method was used for monitoring acrylamide in 406 samples. Acrylamide amounts ranged from <32 to 2450 μg kg-1. A total of 360 samples (89%) were contaminated with acrylamide, but only 14% of the samples exceeded the benchmark levels of the EU legislation. Foods with the highest me...Continue Reading

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Citations

Jun 11, 2020·Clinical and Experimental Reproductive Medicine·Morteza AnvariMajid Pourentezari
Sep 30, 2020·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Burhan Basaran, Ferid Aydin
Feb 7, 2021·Environmental Science and Pollution Research International·Neda Mollakhalili-MeybodiMasoumeh Arab
May 1, 2021·International Journal of Environmental Research and Public Health·Cristina SarionAdriana Dabija

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Methods Mentioned

BETA
solid phase extraction
chips

Software Mentioned

ImproRisk ©
IMPROVAST
ImproRisk
MS Excel

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