PMID: 616022Feb 1, 1977Paper

Determination of coagulation factors (II-VII-X) and kaolin partial thromboplastin time by the LKB 8600 Reaction Rate Analyser

Scandinavian Journal of Clinical and Laboratory Investigation
B Hjorth, E Kjaersgaard

Abstract

Testing of a modified Reaction Rate Analyser 8600 in the automatic determination of coagulation time was accomplished with the assays Thrombotest Normotest and Kaolin Partial Thromboplastin Time. Variations in extinctions, from the adding of start reagent until coagulation, were recorded. The coagulation activities, found by the automatic method for the assays Thrombotest and Normotest, were compared with a manual method. Thrombotest showed a good correlation: 0.30 greater than P greater than 0.25 (paired t test). Normotest showed significantly different values by the methods: P less than 0.001 (paired t test). Kaolin Partial Thromboplastin Time (Activated Partial Thromboplastin Time with kaolin as activator) gave significantly lower vales--the difference was 3 sec--compared with a manual method, and the precision was considerably improved.

Citations

Apr 11, 2000·Research in Veterinary Science·S E ToddR N Ward

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