PMID: 220247Jun 10, 1979

Determination of cooperative interaction between clusters in Clostridium pasteurianum 2 (4Fe-4S) ferredoxin

The Journal of Biological Chemistry
W V Sweeney, B A McIntosh


The effect of reducing one 4Fe-4S cluster in Clostridium pasteurianum 2 (4Fe-4S) ferredoxin on the reduction potential of the unreduced cluster has been investigated. While such an effect is suggested by both the x-ray structure of Peptococcus aerogenes 2 (4F-4S) ferredoxin and the polypeptide conformational change on reduction present in clostridial-type 2 (4Fe-4S) ferredoxins, present studies indicate that cluster-cluster cooperative interaction is not strong enough to be of functional importance in these proteins.

Related Concepts

Clostridium pasteurianum
Plain X-ray
Ferredoxin Activity
Macromolecular Alteration
Peptostreptococcus asaccharolyticus
X-Ray Diffraction
Radiographic Imaging Procedure

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