Determination of fipronil and its metabolites in chicken egg, muscle and cake by a modified QuEChERS method coupled with LC-MS/MS

Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
Qiaozhen GuoBing Shao

Abstract

An easy-to-use method for determining the levels of fipronil and its metabolites (fipronil-desulfinyl, fipronil-sulfone and fipronil-sulfide) in chicken egg, muscle and cake was developed and validated using a modified quick, easy, cheap, effective, rugged and safe (QuEChERS) approach coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis. The samples were extracted using acetonitrile, salted out with sodium chloride at -20°C, and then purified by combined PSA and C18 phases and anhydrous magnesium sulphate. The recoveries were 80.4-119% with relative standard deviations (RSDs) < 10% for the different matrixes. The validated method was used to analyse the target compounds in 214 real samples collected in Beijing. The metabolite fipronil-sulfone was detected in most of the samples and was identified as the main residue in the egg and cake. The method was validated using a proficiency test for fipronil in products of animal origin published by Wageningen University & Research in 2017.

References

Jul 19, 2001·Journal of Chromatography. a·J L VílchezA Navalón
Aug 9, 2011·Journal of Chromatography. a·Carmen FerrerA R Fernández-Alba
May 23, 2014·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Yelko Rodríguez-CarrascoHouda Berrada
Jan 2, 2015·Bulletin of Environmental Contamination and Toxicology·Anil DuhanSaroj Duhan
Jan 21, 2015·Toxicology and Industrial Health·Nalan Yildirim, Guleray Agar
Feb 11, 2015·Journal of Agricultural and Food Chemistry·Minghui LiLijun Han
Feb 13, 2016·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Meiyu ZhangLimin He

❮ Previous
Next ❯

Citations

May 28, 2019·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Cecilia TestaGianfranco Brambilla
Jun 6, 2020·Food Additives & Contaminants. Part B, Surveillance·Banu AkgünRemziye Zengingönül Gökçay
Oct 20, 2020·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Herbert MusarurwaNikita T Tavengwa
Jan 29, 2021·Food Science of Animal Resources·Keguang HanNairui Huo
Nov 6, 2018·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Daniel Blascke CarrãoAnderson Rodrigo Moraes de Oliveira

❮ Previous
Next ❯

Software Mentioned

Lab Solutions
QuEChERS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.