Determination of interval cancer rates in the German mammography screening program using population-based cancer registry data

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
I Urbschat, O Heidinger

Abstract

The evaluation of interval cancers (ICA) and false-negative diagnoses (FND) is important for the quality assurance of the mammography screening program (MSP) for women aged 50-69 years. We aimed to investigate ICA in the states of Lower Saxony (NDS) and North Rhine-Westphalia (NRW). ICA could be identified by record linkage of data from screening attendees (TN) with data from population-based cancer registries. The frequencies of ICA and FND are described, and problems in the categorization of ICA according to EU guidelines are discussed. Record linkage in the cancer registries was performed with the encrypted data from 83,724 TN in NDS and 885,940 TN in NRW. ICA were identified; in NDS, ICA were categorized by the regional MSP reference center. In all, 208 ICA in NDS and 2.018 ICA in NRW were ascertained. In relation to the regional background incidence rate (IR), the relative ICA rates were 22.5%/26.7% in the first year after screening (recommendation of EU guidelines <30% of IR) and 55.6%/54.2% in the second year after screening (recommendation of EU guidelines <50% of IR). It was found that 17.3% of all categorized ICA in NDS were FND (recommendation of EU guidelines <20%). The relative ICA rates for the 2-year interval are...Continue Reading

References

May 19, 2005·Journal of the National Cancer Institute·Johannes D M OttenRoland Holland
Nov 21, 2007·Annals of Oncology : Official Journal of the European Society for Medical Oncology·N PerryL von Karsa
Dec 17, 2009·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·Sven TörnbergAntonio Ponti

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Citations

Oct 18, 2018·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Ulrike HaugHajo Zeeb
Nov 14, 2018·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz·Beate BokhofHans-Werner Hense

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