Determination of metals and pharmaceutical compounds released in hospital wastewater from Toluca, Mexico, and evaluation of their toxic impact

Environmental Pollution
Itzayana Pérez-AlvarezMarcela Galar-Martínez

Abstract

Due to the activities inherent to medical care units, the hospital effluent released contains diverse contaminants such as tensoactives, disinfectants, metals, pharmaceutical products and chemical reagents, which are potentially toxic to the environment since they receive no treatment or are not effectively removed by such treatment before entering the drain. They are incorporated into municipal wastewater, eventually entering water bodies where they can have harmful effects on organisms and can result in ecological damage. To determine the toxicological risk induced by this type of eflluents, eight metals and 11 pharmaceuticals were quantified, in effluent from a hospital. Developmental effects, teratogenesis and oxidative stress induction were evaluated in two bioindicator species: Xenopus laevis and Lithobates catesbeianus. FETAX (frog embryo teratogenesis assay-Xenopus) was used to obtain the median lethal concentration (LC50), effective concentration inducing 50% malformation (EC50), teratogenic index (TI), minimum concentration to inhibit growth (MCIG), and the types of malformation induced. Twenty oocytes in midblastula transition were exposed to six concentrations of effluent (0.1, 0.3, 0.5, 0.7, 0.9, 1%) and negative a...Continue Reading

Citations

Sep 29, 2020·Environmental Science and Pollution Research International·Melissa Valdez-CarrilloConcepción Carreón-Diazconti
Mar 5, 2020·Journal of Water and Health·Asma BeltifaHedi Ben Mansour
Jul 14, 2020·Archives of Microbiology·Emel Mataraci-KaraBerna Ozbek-Celik
Nov 14, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Daniele Sadutto, Yolanda Picó
May 17, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Livier Sánchez-AcevesDamià Barceló
Jun 9, 2021·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Itzayana Pérez-AlvarezGermán Chamorro-Cevallos

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