Determination of monoamines in rat brain regions after chronic administration of lithium.

Neurochemical Research
M CasadoC Giménez

Abstract

The effect of chronic administration of lithium on the concentration of biogenic amines and some of their metabolites in striatum, hippocampus, hypothalamus, pons-medulla and parietal cortex of rat were studied. Longterm lithium treatment modifies significantly the content of indoleamines in striatum and hypothalamus with minor changes in other structures. Catecholamine levels change after the treatment in striatum, hypothalamus, pons-medulla and parietal cortex. These results indicate that lithium treatment at therapeutic doses selectively modifies the catecholamine and indoleamine contents in discrete areas of the brain.

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Citations

Dec 1, 1991·Biological Psychiatry·T TeraoK Abe
Aug 26, 2006·Drug and Chemical Toxicology·Aparna TandonD K Dhawan
Dec 17, 2008·Nutrition Research·Anshoo Malhotra, Devinder K Dhawan
Mar 15, 2008·Liver International : Official Journal of the International Association for the Study of the Liver·Vijayta Dani ChadhaDevinder Kumar Dhawan

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