Determination of parabens and benzophenone-type UV filters in human placenta. First description of the existence of benzyl paraben and benzophenone-4

Environment International
Jennifer Valle-SistacM Silvia Díaz-Cruz

Abstract

UV filters and parabens (PBs) are chemicals used in daily personal care and hygiene products to protect materials and humans from the adverse effects of UV radiation and to preserve the integrity of the formulation, respectively. Several studies highlight their widespread environmental occurrence and endocrine disrupting effects. However, little is known about human exposure to these compounds. The objective of this study was to investigate the exposure of human embryos and foetuses to endocrine disrupting UV filters and PBs. Placentas from volunteer mothers in Barcelona were collected at delivery after informed, written consent by the pregnant women. UV filters and parabens were analysed by liquid chromatography-tandem mass spectrometry. The excellent performance of the method allowed measuring the target compounds in human placental tissue at low ng/g fresh weight level. The detection frequency of the selected compounds was in the range 17-100%. Benzophenone-1, methyl paraben, butyl paraben and benzyl paraben were detected in all samples. The highest measured concentration corresponded to methyl paraben, 11.77ng/g fresh weight. Reported concentrations of benzophenone-4 and benzyl paraben constitute the first evidence about th...Continue Reading

References

May 3, 2001·Environmental Health Perspectives·M SchlumpfW Lichtensteiger
Jul 12, 2002·Archives of Toxicology·Shinshi Oishi
Nov 7, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S Oishi
Oct 2, 2004·Toxicology·Margret SchlumpfWalter Lichtensteiger
Mar 19, 2005·Environmental Science & Technology·Marianne E BalmerThomas Poiger
Apr 19, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M G SoniG A Burdock
Sep 27, 2005·Toxicology and Applied Pharmacology·Marjoke HeneweerJ Thomas Sanderson
Oct 10, 2006·Toxicology and Applied Pharmacology·Petra Y Kunz, Karl Fent
Jan 5, 2008·Environmental Health Perspectives·Andreas KortenkampThomas Backhaus
Aug 19, 2008·Environmental Health Perspectives·Mary S WolffAntonia M Calafat
Jun 9, 2009·Endocrine Reviews·Evanthia Diamanti-KandarakisAndrea C Gore
Oct 8, 2009·Journal of Agricultural and Food Chemistry·Ana Sanches-SilvaPerfecto Paseiro-Losada
Dec 17, 2009·Environmental Pollution·Karl FentMaja Rapp
Apr 13, 2010·Reproductive Toxicology·Julie BobergUlla Hass
Sep 30, 2010·Environmental Health Perspectives·John D MeekerRuss Hauser
Sep 9, 2011·Environmental Health Perspectives·Claire PhilippatRémy Slama
Dec 6, 2011·Analytical and Bioanalytical Chemistry·M Silvia Díaz-CruzDamià Barceló
Mar 16, 2012·Environmental Science & Technology·Tatsuya KunisueKurunthachalam Kannan
May 1, 2012·The Science of the Total Environment·Pablo Gago-FerreroDamià Barceló
May 23, 2012·International Journal of Andrology·M KrauseK T Drzewiecki
Jun 13, 2012·The Journal of Clinical Endocrinology and Metabolism·Marta DíazLourdes Ibáñez
Jun 19, 2012·The Journal of Allergy and Clinical Immunology·Jessica H SavageCorinne A Keet
Sep 8, 2012·Toxicological Sciences : an Official Journal of the Society of Toxicology·Pan HuLing Zhao
Dec 12, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Ying HuMingwen Qi
Mar 16, 2013·International Journal of Hygiene and Environmental Health·Hanne FrederiksenAnna-Maria Andersson
May 1, 2013·Environmental Science & Technology·Pablo Gago-FerreroDamià Barceló
Jun 28, 2014·Environmental Science & Technology·Benny F G PyckeRolf U Halden
Aug 9, 2015·Fertility and Sterility·Germaine M Buck LouisKurunthachalam Kannan
Sep 15, 2015·Environment International·Benny F G PyckeRolf U Halden
Oct 11, 2015·Environmental Pollution·Mariana B AlonsoDamià Barceló

❮ Previous
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Citations

Apr 14, 2016·Environmental Science and Pollution Research International·Yuli EkowatiIgnasi Rodríguez-Roda
Aug 17, 2016·International Journal of Environmental Research and Public Health·Jiaying WangShulin Zhuang
Oct 30, 2016·Environmental Toxicology and Chemistry·Marta LlorcaDamià Barcelo
Jun 21, 2016·The Science of the Total Environment·Maria Pau Serra-RoigDamià Barceló
Jul 15, 2017·The Science of the Total Environment·Hongzhi ZhaoZongwei Cai
Dec 31, 2019·Photochemistry and Photobiology·Orielia Pria EgambaramSuprakas Sinha Ray
Jul 30, 2020·International Journal of Toxicology·Priya CherianBart Heldreth
Jun 24, 2017·Environmental Science and Pollution Research International·Alinne MizukawaDamià Barceló
Jun 27, 2018·Toxicological Sciences : an Official Journal of the Society of Toxicology·Thomas L GonzalezJames M Rae
Jan 7, 2020·Journal of Applied Toxicology : JAT·Natalia MatwiejczukMałgorzata M Brzóska
Sep 22, 2018·Environmental Science and Pollution Research International·Yue HuangXiaochang C Wang
Mar 7, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Oihana GordobilJalel Labidi
Feb 27, 2018·Environmental Research·Armen A GhazarianKatherine A McGlynn
Sep 28, 2017·Physiological Research·L KolatorovaL Starka
Mar 12, 2021·Archives of Environmental Contamination and Toxicology·Yaghoub HajizadehAwat Feizi
Oct 17, 2020·Critical Reviews in Toxicology·Juliana P PaivaMarcelo de Pádula
Jun 26, 2021·Environmental Research·Reiji KojimaUNKNOWN Japan Environment and Children’s Study Group
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Izabela Narloch, Grażyna Wejnerowska

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