Determination of phenolic compounds in rose hip (Rosa canina) using liquid chromatography coupled to electrospray ionisation tandem mass spectrometry and diode-array detection

Rapid Communications in Mass Spectrometry : RCM
Erlend Hvattum

Abstract

Liquid chromatography coupled with negative and positive electrospray ionisation (ESI) tandem mass spectrometry (MS/MS) and diode-array detection (DAD) was used for determination of phenols in rose hip (Rosa canina) extract. ESI mass spectra of the chromatographically separated phenols gave the molecular weight of the compounds through prominent [M - H](-) ions for most of the compounds and M(+) ions for the anthocyanins. Collision induced dissociation (CID) of the [M - H](-) (or M(+)) precursor ions yielded product ions which determined the molecular weight of the aglycones. In-source fragmentation followed by CID of the resulting deprotonated aglycone ([A - H](-)) provided product ions for the identification of the unconjugated phenols. The identification was based on comparison with product ion spectra of commercial standards. UV-diode-array spectra were used for identity confirmation. This combined approach allowed the identification in rose hip extract of an anthocyanin, i.e. cyanidin-3-O-glucoside, several glycosides of quercetin and glycosides of taxifolin and eriodictyol. Phloridzin was identified, and several conjugates of methyl gallate were also found, one of which was tentatively identified as methyl gallate-rutinos...Continue Reading

References

Dec 1, 1995·The American Journal of Clinical Nutrition·H Sies, W Stahl
Feb 27, 1995·Archives of Internal Medicine·M G HertogS Nedeljkovic
May 1, 1997·The American Journal of Clinical Nutrition·M G HertogD Kromhout
May 8, 1999·Free Radical Biology & Medicine·M R McCall, B Frei
May 25, 1999·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·A Carr, B Frei
May 3, 2000·Lancet·B Halliwell
Jun 23, 2000·Annals of the New York Academy of Sciences·J M Gutteridge, B Halliwell
Feb 13, 2001·The Journal of Nutrition·L PackerG Rimbach
Jun 13, 2001·Journal of the American Society for Mass Spectrometry·N FabreJ Quetin-Leclercq
Jan 1, 1994·Nutrition and Cancer·M G HertogD Kromhout

❮ Previous
Next ❯

Citations

Sep 1, 2004·Journal of the American Society for Mass Spectrometry·Barry D Davis, Jennifer S Brodbelt
Apr 23, 2011·Journal of Agricultural and Food Chemistry·Pablo Gomes FerreiraIone Salgado
May 31, 2014·Journal of Food Science and Technology·Haiying LiuPeng Zhou
May 22, 2007·International Journal of Food Sciences and Nutrition·Ocksook YiDongwuk Cho
Jan 17, 2016·Journal of Food Science·Vlasta CunjaValentina Schmitzer
Jan 13, 2016·Journal of Mass Spectrometry : JMS·Jürgen Schmidt
Apr 2, 2010·Phytochemistry·Christian GoschKarl Stich
Aug 19, 2008·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·E M WenzigR Bauer
May 8, 2007·Journal of Ethnopharmacology·Didem Deliorman OrhanErdem Yesilada
Jul 2, 2005·Molecular Nutrition & Food Research·Kathrin KahleElke Richling
Oct 16, 2008·Journal of Mass Spectrometry : JMS·Raymond March, Jennifer Brodbelt
Apr 4, 2008·Phytotherapy Research : PTR·Cosima ChrubasikSigrun Chrubasik
Feb 9, 2012·Journal of the Science of Food and Agriculture·Staffan C AnderssonKimmo Rumpunen
May 6, 2011·Phytotherapy Research : PTR·Hossein Tayefi-NasrabadiZahra Aghdam
Sep 30, 2004·Free Radical Biology & Medicine·Jeevan K PrasainStephen Barnes
Aug 1, 2006·Journal of Pharmaceutical and Biomedical Analysis·Jaime A YáñezNeal M Davies
Feb 11, 2014·Bioinorganic Chemistry and Applications·Jolanta Pulit, Marcin Banach
Jul 21, 2011·Journal of Ethnopharmacology·Francesca LattanzioEster Speroni
Sep 3, 2013·Food Chemistry·Rafaela GuimarãesIsabel C F R Ferreira
Aug 26, 2014·Food Chemistry·Antonieta RuizClaudia Mardones
Jul 12, 2002·Journal of Mass Spectrometry : JMS
Jan 31, 2020·Journal of Separation Science·Dragana Č Dabić ZagoracMaja M Natić
Jun 18, 2017·Journal of Nutritional Science·A N PancheS R Chandra

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.