Determination of phosphoric acid mono- and diesters in municipal wastewater by solid-phase extraction and ion-pair liquid chromatography-tandem mass spectrometry

Analytical Chemistry
José Benito QuintanaThorsten Reemtsma

Abstract

The first analytical method for the determination of 13 phosphoric acid mono- and diesters from aqueous samples is presented. The method consists of solid-phase extraction (SPE) and ion-pair liquid chromatographic separation with tri-n-butylamine coupled to electrospray ionization tandem mass spectrometry in the negative ion mode. Due to a lack of pure standards, only 3 of the 13 esters could be quantified. SPE recoveries ranged from 71 to 112% for di-n-butyl phosphate, diphenyl phosphate, and di-(2-ethylhexyl) phosphate (DEHP) with limits of quantification from 7 to 14 ng/L for 100-mL samples. At analyte concentrations >or=1 microg/L, aqueous samples can be analyzed by direct injection without extraction. In municipal wastewater, six diesters and one monoester were unambiguously identified by comparison with synthesized reference material. DEHP showed highest concentrations of 60 and 5 microg/L in raw and treated wastewater, respectively. The detection of monoethylhexyl phosphate was confirmed by LC-Q-TOF-MS analysis, and it was found at a concentration level comparable to DEHP. Laboratory degradation tests show that phosphoric acid diesters can be formed as intermediates in the microbial degradation of trialkyl phosphates tha...Continue Reading

References

Sep 11, 2002·Rapid Communications in Mass Spectrometry : RCM·Félix HernándezOscar J Pozo
Mar 31, 2004·Rapid Communications in Mass Spectrometry : RCM·José Benito Quintana, Thorsten Reemtsma
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Citations

May 15, 2012·Analytical and Bioanalytical Chemistry·Alin C DirtuAdrian Covaci
Jul 10, 2012·Journal of Hazardous Materials·Nuno RatolaAthanasios Katsoyiannis
Dec 23, 2011·Chemosphere·Rosario RodilDarío Prada-Rodríguez
Feb 22, 2011·The Science of the Total Environment·Thorsten ReemtsmaStefanie Roegler
Sep 22, 2007·The Science of the Total Environment·Elena Martínez-CarballoOliver Gans
Apr 8, 2015·Chemical Communications : Chem Comm·Wei JiYukihiro Ozaki
Oct 21, 2016·Water Science and Technology : a Journal of the International Association on Water Pollution Research·Long PangHongzhong Zhang
Dec 1, 2006·Journal of Mass Spectrometry : JMS
Jul 1, 2008·Critical Reviews in Analytical Chemistry·Teresa Cecchi
Dec 6, 2020·Scientific Reports·Yin-Chien ChenCho-Chun Hu
Nov 26, 2018·The Science of the Total Environment·Yu WangKurunthachalam Kannan
Dec 31, 2009·Analytical Chemistry·Wan-Ling ChengJyh-Myng Zen
Mar 3, 2020·Langmuir : the ACS Journal of Surfaces and Colloids·Gabriela P RatkovskiCelso P de Melo
May 22, 2018·Environmental Science & Technology·Pablo Gago-FerreroLutz Ahrens
Jan 6, 2009·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Birgit Karin SchindlerJürgen Angerer
Oct 13, 2021·Analytical Methods : Advancing Methods and Applications·Xue GaoJianrong Li

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