Determination of plastic additives in packaging by liquid chromatography coupled to high resolution mass spectrometry

Journal of Chromatography. a
Cristina Moreta, María-Teresa Tena

Abstract

A simple and sensitive analytical method for the determination of several plastic additives in multilayer packaging based on solid-liquid extraction (SLE) and ultra-high performance liquid chromatography (UHPLC) coupled to variable wavelength (VWD) and time of flight mass spectrometry (TOF-MS) detectors is presented. The proposed method allows the simultaneous determination of fourteen additives belonging to different families such as antioxidants, slip agents and light stabilizers, as well as two oxidation products in only 9min. The developed method was validated in terms of linearity, matrix effect error, detection and quantification limits, repeatability and intermediate precision. The instrumental method showed satisfactory repeatability and intermediate precision at concentrations closed to LOQ with RSDs less than 7 and 20%, respectively, and LODs until 5000 times more sensitive than other GC-FID and HPLC-VWD methods previously reported. Also, focused ultrasound solid-liquid extraction (FUSLE) was optimized and evaluated to extract plastic additives from packaging. Extraction results obtained by FUSLE and SLE were compared to those obtained by pressurized liquid extraction (PLE). All extraction methods showed excellent ext...Continue Reading

References

Oct 30, 2003·Journal of Chromatography. a·M S Dopico-GarcíaM V González-Rodríguez
Dec 7, 2005·Journal of Chromatography. a·Alvaro Garrido-López, María Teresa Tena
May 24, 2006·Journal of Chromatography. a·Alvaro Garrido-LópezMaría Teresa Tena
Nov 6, 2007·Journal of Chromatography. a·Alvaro Garrido-LópezMaría Teresa Tena
Nov 19, 2010·Journal of Separation Science·Eva Reingruber, Wolfgang Buchberger
Dec 28, 2010·Journal of Chromatography. a·Cristina Moreta, María Teresa Tena

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Citations

Mar 22, 2016·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Rafael Paseiro-CerratoRoland Franz
Jun 11, 2016·Journal of Hazardous Materials·Barbara Vé Wiewel, Marja Lamoree
Aug 9, 2016·Analytica Chimica Acta·Christian W Klampfl, Markus Himmelsbach
Apr 13, 2017·Journal of Separation Science·Georg Kreisberger, Wolfgang W Buchberger
Mar 23, 2019·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Bo Li
Feb 14, 2020·Chemosphere·Guomao ZhengAmina Salamova

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