Determination of red blood cell superoxide dismutase and glutathione peroxidase in newborns in relation to neonatal hemolysis

Clinica Chimica Acta; International Journal of Clinical Chemistry
G RotilioM Brunori


Superoxide dismutase and glutathione peroxidase activities have been determined in newborns. Their mean values are approximately the same as in normal adults. In some cases a low content of superoxide dismutase and/or a high (superoxide dismutase/glutathione peroxidase) ratio are associated with hematological symptoms. In addition, a low superoxide dismutase activity is associated with hyperbilirubinemia and is present in two of the three cases showing maximal acetylphenylhdrazine-induced hemoloysis.


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Related Concepts

Selenoglutathione Peroxidase
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