Determination of strength and deformation behavior of human cartilage for the definition of significant parameters

Journal of Biomedical Materials Research. Part a
W GrellmannC Bierögel

Abstract

In reconstructive surgery, an artificial supporting scaffold made from autogenous cartilage from the rib, the ear concha, or the nasal septum is used as a substitute for the destroyed endogenous tissue in the ear concha, the nose, the trachea, and in parts of the facial skeleton. For the successful use of polymer materials in reconstructive surgery, an exact knowledge of the material properties of the natural tissues is required. The applicability of conventional material test methods was examined with regard to the suitability of the test methodology. Materials properties are to be assessed for different specimen sizes and geometries. Human cartilage specimens from the septum, rib, and ear were subsected to the following test methods: (1) tension, (2) bending, (3) compression, and (4) micro-hardness measuring. Specimen geometry was evaluated for each experimental method by taking into account the dimensions of samples used in plastics testing as well as the appropriate model of miniaturization. Elastic properties determined using test methods (1), (2), and (3) are Et-sep=(7.2+/-3.4) MPa, Ef-rib=(8.8+/-2.9) MPa, and Ec-rib=(103+/-30) MPa. The micro-hardness values hpl fluctuate for septum from 1 to 4 N/mm2 and for the rib from ...Continue Reading

Citations

May 6, 2008·Tissue Engineering. Part C, Methods·Chen-Huan LinShan-Hui Hsu
Aug 11, 2011·Tissue Engineering. Part B, Reviews·David A BicharaMark A Randolph
Nov 26, 2013·Journal of Biomechanics·Ayman A Al Dayeh, Susan W Herring
Mar 13, 2014·The Journal of the Acoustical Society of America·Martin K BrummundFrédéric Laville
Nov 19, 2014·BioMed Research International·Bin YangHeow-Pueh Lee
Jan 17, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Jason P CaffreyDeborah Watson
Jan 2, 2009·Journal of Biomechanics·Gregory M WilliamsRobert L Sah
May 13, 2009·Journal of Morphology·Ayman A Al DayehSusan W Herring
Aug 9, 2011·Microscopy Research and Technique·Yang XiaJihyun Lee
Nov 19, 2011·Journal of Tissue Engineering and Regenerative Medicine·Adelola OseniAlexander M Seifalian
Jun 22, 2010·The Laryngoscope·Shu Jin LeeHeow Pueh Lee
Feb 28, 2014·International Journal for Numerical Methods in Biomedical Engineering·Kwong Ming TseHeow Pueh Lee
Jan 13, 2015·Mayo Clinic Proceedings·Ayushman SharmaGrant S Hamilton
Dec 18, 2013·Computer Methods in Biomechanics and Biomedical Engineering·Kwong Ming TseHeow Pueh Lee
Jul 2, 2015·Journal of the Korean Association of Oral and Maxillofacial Surgeons·Valdir Cabral AndradeJose Ricardo Albergaria-Barbosa
Mar 14, 2019·The Annals of Otology, Rhinology, and Laryngology·Nikita GuptaJames C Iatridis
Nov 22, 2011·Biomedical Materials·Amine HarraneBenjamin Nottelet
May 1, 2015·JAMA Facial Plastic Surgery·James Hakjune KimBrian J F Wong
Apr 29, 2016·JAMA Facial Plastic Surgery·Eric GrayBrian J F Wong
Apr 24, 2013·Bone & Joint Research·Y Xia
Jul 16, 2016·Annals of Biomedical Engineering·M F GriffinP E M Butler
Aug 30, 2019·Scientific Reports·Zita M JessopIain S Whitaker
Dec 5, 2016·The Journal of the Acoustical Society of America·You ChangStefan Stenfelt
Mar 7, 2020·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Fay PenroseNathan Jeffery
Jul 2, 2021·Scientific Reports·Matthias WeberAnja Niehoff
Jul 28, 2021·Aesthetic Plastic Surgery·Yanyan CaoYonghuan Zhen

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