Determination of susceptibilities of 26 Leptospira sp. serovars to 24 antimicrobial agents by a broth microdilution technique

Antimicrobial Agents and Chemotherapy
Clinton K Murray, Duane R Hospenthal

Abstract

The MICs of 24 antimicrobials for 26 Leptospira spp. serovars were determined using a broth microdilution technique. The MICs at which 90% of isolates tested were inhibited (MIC(90)s) of cefepime, imipenem-cilastatin, erythromycin, clarithromycin, and telithromycin were all </=0.01 microg/ml. The MIC(90)s of amoxicillin, aztreonam, cefdinir, chloramphenicol, and penicillin G were >/=3.13 microg/ml. Many antimicrobials have excellent in vitro activity against Leptospira.

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Citations

Feb 2, 2006·Current Infectious Disease Reports·Jessica N Ricaldi, Joseph M Vinetz
Nov 1, 2006·Current Opinion in Infectious Diseases·Matthew E GriffithClinton K Murray
Apr 16, 2008·Antimicrobial Agents and Chemotherapy·Roseanne A RessnerClinton K Murray
May 2, 2007·Antimicrobial Agents and Chemotherapy·Matthew E GriffithClinton K Murray
Sep 22, 2010·Antimicrobial Agents and Chemotherapy·Antara ChakrabortyShin-Ichi Yoshida
May 26, 2006·Antimicrobial Agents and Chemotherapy·James E MoonClinton K Murray
Nov 2, 2012·Antimicrobial Agents and Chemotherapy·Vanaporn WuthiekanunSharon J Peacock
Apr 9, 2010·Journal of Clinical Microbiology·Gerald L MurrayBen Adler
Jul 23, 2013·BMC Complementary and Alternative Medicine·Weeranuch SeesomWasana Sukhumsirichart
Nov 4, 2011·The American Journal of Tropical Medicine and Hygiene·Brande M HarrisDuane R Hospenthal
Dec 17, 2008·Veterinary Microbiology·Nicholas J EvansStuart D Carter
Dec 20, 2007·Equine Veterinary Journal·T J DiversW S Schwark
Nov 7, 2006·International Journal of Antimicrobial Agents·Georgios Pappas, Antonio Cascio
Mar 31, 2015·American Journal of Veterinary Research·Sara Melisa Arciniegas RuizDinorah Vargas Estrada
Sep 20, 2016·European Journal of Medicinal Chemistry·Andivelu IlangovanKalimuthusamy Natarajaseenivasan
Jun 10, 2015·The American Journal of Tropical Medicine and Hygiene·Vanaporn WuthiekanunSharon J Peacock
Nov 15, 2018·Journal of the American Animal Hospital Association·Tara Mauro, Kenneth Harkin
Mar 18, 2020·Infectious Diseases·Despoina GkentziStelios F Assimakopoulos
Feb 5, 2019·Journal of Veterinary Pharmacology and Therapeutics·Jesús MendozaHector Sumano
Aug 6, 2020·Antibiotics·Fabrizio BertelloniFilippo Fratini
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Apr 4, 2021·International Journal of Environmental Research and Public Health·Che Ain Munirah IsmailNabilah Ismail

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