Determination of technical grade isocyanates used in the production of polyurethane plastics

Journal of Environmental Monitoring : JEM
Asa MarandMarianne Dalene

Abstract

A method for determination of technical grade isocyanates used in the production of polyurethane (PUR) is presented. The isocyanates in technical grade products were characterised as di-n-butylamine (DBA) derivatives using LC-MS and LC-chemiluminescent nitrogen detection (CLND) and the total isocyanate content was compared to a titration assay. For collection of isocyanates in air, an impinger-filter sampling technique with DBA as derivatisation reagent was used. Characterised DBA and nonadeuterium labelled DBA derivatives of isocyanates in technical products were used as calibration standards and internal standards, respectively, in the analysis of air samples. Three workplaces were studied where PUR products were produced either by spraying or by moulding. In both technical products and in air samples, a number of monomeric, oligomeric and prepolymeric isocyanates of e.g. methylenebisphenyl diisocyanate (MDI) and hexamethylene diisocyanate (HDI) were characterised. Several of these have not previously been described in workplace atmospheres. In the technical isocyanate products, between 69 and 102% of the NCO content determined by titration was accounted for by LC-CLND. Quantifications of a wide range of isocyanates in air sa...Continue Reading

Citations

Nov 15, 2006·Analytical and Bioanalytical Chemistry·Hartmut HennekenUwe Karst
Sep 17, 2009·Journal of Occupational and Environmental Hygiene·Carrie A RedlichRobert P Streicher
Dec 28, 2011·The Annals of Occupational Hygiene·John WhiteMatthew Coldwell
Dec 29, 2013·The Annals of Occupational Hygiene·Daniel GylestamGunnar Skarping
Mar 31, 2005·Journal of Environmental Monitoring : JEM·Asa MarandGunnar Skarping
Apr 1, 2010·Drug Testing and Analysis·E GallardoJ A Queiroz

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