PMID: 8376519Jul 2, 1993Paper

Determination of tenoxicam in plasma by high-performance liquid chromatography

Journal of Chromatography
M I Múnera-Jaramillo, S Botero-Garcés

Abstract

A high-performance liquid chromatographic technique with a lower detection limit for measuring tenoxicam plasma levels was standardized. Tenoxicam was extracted with dichloromethane from acidified plasma and the evaporated extracts were analysed on a reversed-phase column using a methanol-phosphate buffer mobile phase and setting ultraviolet detection at 355 nm. A reproducible calibration curve in the 5-2000 ng/ml range was obtained. The mean recovery of extraction was 98.99 +/- 4.3% and the detection limit was 5 ng/ml.

References

Jun 13, 1991·The New England Journal of Medicine·P M Brooks, R O Day
Jan 10, 1986·Journal of Chromatography·P HeizmannK Zinapold

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Citations

Mar 24, 1995·Journal of Chromatography. B, Biomedical Applications·J L Mason, G J Hobbs
Jun 5, 1998·Journal of Chromatography. B, Biomedical Sciences and Applications·S Radhofer-Welte, P Dittrich
Mar 4, 2000·Journal of Pharmaceutical and Biomedical Analysis·M S GarcíaM J Gimenez
Dec 4, 2012·Indian Journal of Pharmaceutical Sciences·S ChandelC J Kapadia
Dec 5, 2006·Journal of Pharmaceutical and Biomedical Analysis·Iulia SoraAndrei Medvedovici

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