Determination of the in vitro and in vivo antimicrobial activity on salivary Streptococci and Lactobacilli and chemical characterisation of the phenolic content of a Plantago lanceolata infusion

BioMed Research International
Gianmaria Fabrizio FerrazzanoAntonino Pollio

Abstract

Introduction. Plant extracts may be suitable alternative treatments for caries. Aims. To investigate the in vitro and in vivo antimicrobial effects of Plantago lanceolata herbal tea (from flowers and leaves) on cariogenic bacteria and to identify the major constituents of P. lanceolata plant. Materials and Methods. The MIC and MBC against cariogenic bacteria were determined for P. lanceolata tea. Subsequently, a controlled random clinical study was conducted. Group A was instructed to rinse with a P. lanceolata mouth rinse, and Group B received a placebo mouth rinse for seven days. The salivary colonisation by streptococci and lactobacilli was investigated prior to treatment and on the fourth and seventh days. Finally, the P. lanceolata tea was analysed for its polyphenolic content, and major phenolics were identified. Results and Discussion. P. lanceolata teas demonstrate good in vitro antimicrobial activity. The in vivo test showed that Group A subjects presented a significant decrease in streptococci compared to Group B. The phytochemical analysis revealed that flavonoids, coumarins, lipids, cinnamic acids, lignans, and phenolic compounds are present in P. lanceolata infusions. Conclusions. P. lanceolata extract could repres...Continue Reading

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Dec 5, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Gianmaria F FerrazzanoGiuseppe Palumbo

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Citations

Dec 30, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gianmaria Fabrizio FerrazzanoAntonino Pollio
Aug 5, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gianmaria Fabrizio FerrazzanoMaria Grazia Volpe
Dec 7, 2017·BioMed Research International·Gianmaria Fabrizio FerrazzanoCaterina Pagliarulo
Jan 11, 2018·Journal of Ethnobiology and Ethnomedicine·Muhammad Abdul AzizRiaz Ullah
Jun 12, 2018·Journal of Oral Microbiology·Helena BarrosoSamanta Maci
Oct 20, 2020·Frontiers in Pharmacology·Dâmaris SilveiraMichael Heinrich
Nov 12, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gianmaria Fabrizio FerrazzanoTiziana Cantile
Mar 9, 2021·Dental Materials Journal·Sabrina FeitosaSimone Duarte
Aug 28, 2021·Evidence-based Complementary and Alternative Medicine : ECAM·Najwan JubairAyesha Fatima

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Software Mentioned

SPSS
Statistical Package for Social Sciences
Analyst

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