Jul 1, 1977

Determination of the intensity of antimicrobial immunity in diphtheria during an acute experiment

Zhurnal mikrobiologii, epidemiologii, i immunobiologii
M O Birger, L V Griazeva

Abstract

The authors elaborated a method of determination of the antimicrobial immunity intensity in diphtheria in an acute experiment: guinea pigs were infected with a virulent culture of Corynebacterium diphtheriae grown on agar with iron in a concentration depressing the toxinogenesis. A temporary absence of the toxin formation permitted to evaluate the antibacterial immunity except the antitoxic one. Guinea pigs preimmunized with somatic Corynebacterium diphtheriae antigen or an immune antimicrobial serum constituted the experimental group. The antimicrobial protection level was assessed by the difference in the mortality rate of guinea pigs in the experimental and control groups.

  • References
  • Citations

References

  • We're still populating references for this paper, please check back later.
  • References
  • Citations

Citations

  • This paper may not have been cited yet.

Mentioned in this Paper

Corynebacterium diphtheriae Antigen
Agar
Cavia
Acute Disease
Toxin Biosynthetic Process
Corynebacterium diphtheriae
Antibodies, Bacterial
Microbicides
Anti-Bacterial Agents
Cavia porcellus

About this Paper

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Bone Marrow Neoplasms

Bone Marrow Neoplasms are cancers that occur in the bone marrow. Discover the latest research on Bone Marrow Neoplasms here.

IGA Glomerulonephritis

IgA glomerulonephritis is a chronic form of glomerulonephritis characterized by deposits of predominantly Iimmunoglobin A in the mesangial area. Discover the latest research on IgA glomerulonephritis here.

Cryogenic Electron Microscopy

Cryogenic electron microscopy (Cryo-EM) allows the determination of biological macromolecules and their assemblies at a near-atomic resolution. Here is the latest research.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

LRRK2 & Immunity During Infection

Mutations in the LRRK2 gene are a risk-factor for developing Parkinson’s disease. However, LRRK2 has been shown to function as a central regulator of vesicular trafficking, infection, immunity, and inflammation. Here is the latest research on the role of this kinase on immunity during infection.

Antiphospholipid Syndrome

Antiphospholipid syndrome or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by the presence of antibodies directed against phospholipids.

Meningococcal Myelitis

Meningococcal myelitis is characterized by inflammation and myelin damage to the meninges and spinal cord. Discover the latest research on meningococcal myelitis here.

Alzheimer's Disease: MS4A

Variants within membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease by recent genome-wide association studies. Here is the latest research.

Related Papers

Zhurnal mikrobiologii, epidemiologii, i immunobiologii
G G KharseevaO I Sylka
Zhurnal mikrobiologii, epidemiologii, i immunobiologii
G G Kharseeva, E P Moskalenko
© 2020 Meta ULC. All rights reserved