Determination of the packed cell volume using 131I-human serum albumin

British Journal of Haematology
J M England, M C Down

Abstract

When trace quantities of labelled albumin have been added to blood, the packed cell volume (PCV) may be determined by isotope counting using the relationship: (plasma counts-blood counts)/(plasma counts). This method for measuring the PCV is not affected by plasma trapping between the red cells and the results do not depend upon the centrifugation conditions. The PCV determination with labelled albumin has a high precision (coefficient of variation = 0.9%) and there is very good agreement with the centrifugation PCV using Wintrobe tubes after this measurement has been corrected for plasma trapped between the red cells. No significant compression of the red cells occurred when the blood samples were centrifugated in Wintrobe PCV tubes.

References

Aug 1, 1972·British Journal of Haematology·J M EnglandD A Waters
Jan 1, 1969·The International Journal of Applied Radiation and Isotopes·J M England, R G Miller
Aug 1, 1965·Proceedings of the Society for Experimental Biology and Medicine·S ChienM I Gregersen
Dec 1, 1956·Journal of Cellular Physiology·R GUTTMAN, M M GROSS
Jan 1, 1961·Scandinavian Journal of Clinical and Laboratory Investigation·L GARBY, J C VUILLE
Mar 1, 1965·Journal of Clinical Pathology·C ECONOMOU-MAVROU, C TSENGHI

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Citations

Mar 1, 1976·British Journal of Haematology·J M England, M C Down
May 1, 2001·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·B P KelleherS D O'Broin
Jan 1, 1982·Clinical and Laboratory Haematology·D L Guthrie, T C Pearson
Jul 1, 1986·Annals of Clinical Biochemistry·A J LombartsB Leijnse

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