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Determination of trimethylsilyl methylated nucleic acid bases in urine by gas-liquid chromatography

Journal of Chromatography

Jan 7, 1976

D B LakingsT P Waalkes

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Abstract

A method for the determination of the urinary excretion level of methylated nucleic acid bases by gas-liquid chromatography (GLC) has been developed. A clean-up procedure prior to GLC analysis consisted of hydrolysis, filtration, charcoal adsorption, and anion exchange. Studies to deter...read more

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TRNA Methyltransferases
Hydrolysis
Nucleic Acids
Transfer RNA
Study, Methodological
Guanine
Hydrogen-Ion Concentration
Primary Malignant Neoplasm
Methylate
Nucleic Acid Location
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  • Determination of trimethylsilyl methylated nucleic acid bases in urine by gas-liquid chromatography

    Journal of Chromatography

    Jan 7, 1976

    D B LakingsT P Waalkes

    PMID: 1411

    DOI: 10.1016/s0021-9673(00)83701-2

    Abstract

    A method for the determination of the urinary excretion level of methylated nucleic acid bases by gas-liquid chromatography (GLC) has been developed. A clean-up procedure prior to GLC analysis consisted of hydrolysis, filtration, charcoal adsorption, and anion exchange. Studies to deter...read more

    Mentioned in this Paper

    TRNA Methyltransferases
    Hydrolysis
    Nucleic Acids
    Transfer RNA
    Study, Methodological

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